Protein Alignment Gle1 and gle1

DIOPT Version :10

• Sequence 1: NP_610400.1
• Gene: Gle1 / 35849
• FlyBaseID: FBgn0033316
• Length: 677
• Species: Drosophila melanogaster
• Sequence 2: XP_002935547.1
• Gene: gle1 / 100491445
• XenbaseID: XB-GENE-972613
• Length: 687
• Species: Xenopus tropicalis
• Alignment Length: 658
• Identity: 172/658 - (26%)
• Similarity: 308/658 - (46%)
• Gaps: 109/658 - (16%)

  Fly    72 DFEPNISCFPDLQAINASIVRRELEEEGKRCVRQQLKAIRDKQDAMRLSRETQ---QRKEERQRD 133
            |||.:.|.|         ::::..|..     :..:||....:....:|.|.:   ....|.:|.
 Frog    85 DFETDFSDF---------VIKKTPESH-----QDSMKAETSPKLLSEISAEVEGSIYLYREAERI 135

  Fly   134 QLQQKALRERNESLLIQK--ADQMT------AAQLEAQQREQLALRQQIDQKLHKLALEGVSRCQ 190
            ::|.|..:.....:..:|  |||.|      ...:|.:||::   |.::.::|.:.:.|.:.: |
 Frog   136 KMQNKIQKRLEMFVQYEKNFADQATEQLKRFEEMMELKQRQE---RDRLQEQLEEGSKEALGQ-Q 196

  Fly   191 RRFNQKYEGIAKILLSLNPETVKVCAAQNTQLKELGQK--FEQLVSSVKMGN------CEMQSQF 247
            .:..:::...||:|              |.:|:|..|:  .||.....:.|.      |.:|.:.
 Frog   197 EKLKEEHRTRAKLL--------------NRKLREAEQQRHLEQERIRQEEGRDRERRLCFLQQEV 247

  Fly   248 LCSIIKAEEFCKSLDALELD-------------IIKQLAEFSEQ----IQQQLKMEAAKKLEDER 295
            |..:.:.|...|..:.|.:|             |:..:...|||    .|:.:.:       .||
 Frog   248 LQLVQQIEVDYKHQETLRMDLSAYSQRGNQICGILSSVVRSSEQSGFPTQEDVNV-------GER 305

  Fly   296 QRQQQQ------EEERQKLEEQQKLEEQEKLRKEKEESAAKEKQQEAETAKADAANVPAPLEPKS 354
            ..|:.|      ::|....||::|.||..:..|:||    .||||....|.|     ||....||
 Frog   306 SLQEMQALVSSMQKEVSAAEERRKAEEVAERVKQKE----LEKQQTKAQAPA-----PAQTHQKS 361

  Fly   355 QDVPPAATATSTSVHPDRLKFYNDILALYQSKVDAVKPLQ--TEESLKQYRTGCQRAINLPLNAI 417
            |     .........|..:|.|..:..:.:..::...|||  .:..:|..|...|:||.:|::.|
 Frog   362 Q-----KEGLQEKASPCIMKSYQQLQNMCEQSLNDFAPLQDARDPKVKAIRGDLQKAIYIPVSQI 421

  Fly   418 SAVSPQHLAQNFDKLYSFFAGQPTKVMNGT-ITINDHPLARDYCMLLMAKKFVSQTETAICSNPQ 481
            |:.:..:|.:.|:||.:...|:.......: |:::.||.|.|:....:|:|.|.|.|..|.|:.:
 Frog   422 SSKAGSNLKEIFEKLNNLLLGKRVSSFGSSMISVSQHPQALDFVYYKLAEKLVKQGEEEIASHHE 486

  Fly   482 AAFPFASVIITFWKLLPDFGKVFLAYMYKESPFLVPYVIPQQQGQTPEQYLKTIGYRLTDKNELE 546
            ||||.|:|....|:..|..|::|||::||:.|:.:|:....::|.:.|:|.:.:||::.| :::|
 Frog   487 AAFPIAAVASGIWEHHPKVGELFLAHLYKKCPYALPFYPAFKEGTSIEEYQRILGYKVED-SQVE 550

  Fly   547 KPDIYLKRQTGLARLYAAVI----ISQGRKAAGPDECFELNEGWLWLAHMVHVKPLPDISATLIM 607
            :.|.:|||.:|:.||||||:    ....::.:.|   ..||..|.||..:::::|:.||::||:.
 Frog   551 QQDNFLKRMSGMIRLYAAVMQIRWYYSNKQESHP---HGLNYAWQWLGQLLNMEPVADITSTLLY 612

  Fly   608 EILQTLGFELWRTYGKQFVKLLVYIQNIYMPQ---LAAYDEGGPKTRLEMLLAKFLRERQIAQAV 669
            :.|:..|..|.:||..||.|||:.|:|.|:|:   ::...:.|..|||.:.|...:::.:|....
 Frog   613 DFLEVCGNALMQTYHFQFWKLLLLIKNEYLPRIEIISTSAQMGSVTRLRLFLENSIKKNEIPLPK 677

  Fly   670 GVLPPGFW 677
            |.|...||
 Frog   678 GYLSQSFW 685

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gle1	NP_610400.1	Smc	<82..>232	CDD:440809	29/162 (18%)
		EnvC	104..>365	CDD:443969	66/302 (22%)
		GLE1	394..633	CDD:462280	81/245 (33%)
gle1	XP_002935547.1	PTZ00121	<107..370	CDD:173412	66/301 (22%)
		GLE1	400..638	CDD:462280	80/241 (33%)