DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment beta3GalTII and b3galt6

DIOPT Version :9

Sequence 1:	NP_610399.1	Gene:	beta3GalTII / 35848	FlyBaseID:	FBgn0033315	Length:	382	Species:	Drosophila melanogaster
Sequence 2:	NP_001038690.1	Gene:	b3galt6 / 572324	ZFINID:	ZDB-GENE-101104-13	Length:	335	Species:	Danio rerio

Alignment Length:	373	Identity:	127/373 - (34%)
Similarity:	172/373 - (46%)	Gaps:	89/373 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 FLTKILSSVDQCPAHRSRIPHLEPHP------------NLFLMVLVLSAPHNADERNAMRRTWLA 74
            ||.|..|...:........|..|.|.            :.||::|:.:.|...:.|:.:|.|||.
Zfish    28 FLAKCTSETLKPAESPGAAPQAESHQKPPAGPARPKELSAFLVILITTGPKYTERRSIIRSTWLT 92

  Fly    75 NAGQSIAQPYLPEELIYLPTFNAQGHLQVELVAEQASRLRQYTNWQQSLLTEGPPRTKRLITVKH 139
            .        :.||.|.:
Zfish    93 K--------HDPEVLYW------------------------------------------------ 101

  Fly   140 VFSIGTLDLSSSALAELEKEQNQNNDLLLLNRHHDTYKNLTAKLMQSLYILRRHYEFSYMLKVDD 204
             |.|||..|.:..|..|..||.:::|||||....|:|:|||.||:.....|.::.||.::||.||
Zfish   102 -FVIGTEGLPAEDLQNLATEQIRHHDLLLLPDLRDSYENLTQKLLHMYSWLDQNVEFKFVLKADD 165

  Fly   205 DTYVKLDSLVNTLVSYDRKLLRKRSEYRDHVLPQLYWGYFNGRSTIKTKGQWKESSYYLSKNYLP 269
            ||:.:||.|...|         |..|.::    :||||:|:||..:||.|:||||::.|...|||
Zfish   166 DTFARLDLLKEEL---------KVKEPKE----RLYWGFFSGRGRVKTAGKWKESAWELCDYYLP 217

  Fly   270 YALGGGYVLSRSLCDYIVNNSQLLSHYGSEDVSVGTWLAPLRHVYRWHDPRFDTSYAPRKCRSYH 334
            ||||||||||..|..||..|...|..:.|||||:|.||||: .|.|.|||||||.|..|.|.:.:
Zfish   218 YALGGGYVLSADLVRYIRLNVGFLKIWQSEDVSLGAWLAPV-DVKRLHDPRFDTEYKSRGCSNKY 281

  Fly   335 MVLHKRNGQMMRDIH-----DGELCSGIGSSILSDYYYDWTRTADKCC 377
            :|.||::.:.|.:.|     ||.||.......|| |.|||:....:||
Zfish   282 LVTHKQSLEDMLEKHQTLQRDGRLCKEEVKLRLS-YIYDWSVPPSQCC 328

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
beta3GalTII	NP_610399.1	Galactosyl_T	125..319	CDD:304462	82/193 (42%)
b3galt6	NP_001038690.1	Galactosyl_T	81..266	CDD:304462	90/255 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170590482
Domainoid	1	1.000	138	1.000	Domainoid score	I4831
eggNOG	1	0.900	-	-		E1_KOG2288
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H14549
Inparanoid	1	1.050	185	1.000	Inparanoid score	I3928
OMA	1	1.010	-	-		QHG52323
OrthoDB	1	1.010	-	-		D465401at33208
OrthoFinder	1	1.000	-	-		FOG0005027
OrthoInspector	1	1.000	-	-		oto40571
orthoMCL	1	0.900	-	-		OOG6_107698
Panther	1	1.100	-	-	LDO	PTHR11214
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2813
SonicParanoid	1	1.000	-	-		X4084
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.800