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Protein Alignment Cirl and adgrl4

DIOPT Version :9

Sequence 1:	NP_001260807.1	Gene:	Cirl / 35846	FlyBaseID:	FBgn0033313	Length:	1711	Species:	Drosophila melanogaster
Sequence 2:	NP_998532.2	Gene:	adgrl4 / 406676	ZFINID:	ZDB-GENE-040426-2689	Length:	735	Species:	Danio rerio

Alignment Length:	684	Identity:	163/684 - (23%)
Similarity:	284/684 - (41%)	Gaps:	116/684 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   386 TTPA-----PS-GGDCLHNSS-SCEPPVSMAHKVNQRLRNFEPTWHPATPDLTQCRSLWLNNLEM 443
            |:||     |: |.||:.||. .|.    ..||..:...|                    :.||.
Zfish   142 TSPAGPWFMPNHGTDCIENSKIHCH----QDHKCTKETVN--------------------STLER 182

  Fly   444 RVNQRDSSLISIANDMSEVTSSKTLYGGDMLVTTKIIQTVSEKMMHDKETFPDQRQREAMIMELL 508
            ..|      :||:..:.|:....:.....:|:.:.|...||.| ::..:...|.::.   :.|.:
Zfish   183 MTN------LSISERLKEIRYQTSAALSPVLLISYIEAMVSSK-LNSGDVSKDSKEH---VNETI 237

  Fly   509 HCVVKTGSNLLDESQLSSWLDLNPEDQMRVATSLLTGLEYNAFLLADTIIRERSVVQKVKNILLS 573
            ..:|.:.:||:::.:...|..:|.:.:|...|.||...|.....|:........:.....::.:.
Zfish   238 TNLVFSVNNLVEKDEKVEWKKINEDLRMYYVTKLLHTAEKETLALSAGYTHATQMQVHAGDVEMK 302

  Fly   574 VRVLETKTIQSSVVFPDSDQWPLSS----DRIELPRAALIDNSEGGLVRIVFAAFDRLESILKPS 634
            :...|.:..|         :.|||:    :.|.|........:..|...:||..:..:..:|||:
Zfish   303 LYTFEPRQAQ---------KHPLSANIQGNSISLSTKKARHANNNGSTSVVFLIYHSIGDLLKPA 358

  Fly   635 YDHFDLKSSRSYVRNTAILSNDSDVNAGEIQQRLRILNSKVISASLGKGRHIQLSQPITLTLKHL 699
            .|    .....|.|..|         ||||     .:||.||:|::...:.:.|:. :|.||||
Zfish   359 DD----PGVADYSRYAA---------AGEI-----TVNSPVIAAAISNQKTLPLND-VTFTLKH- 403

  Fly   700 KTENVTNPT-----CVFWNY----IDHAWSANGCSLESTNRTHSVCSCNHLTNFAILMDVVDEHQ 755
             |:.: :|.     |.||.|    :.| ||.:||.....|.||:.|||||||:|||||   ...:
Zfish   404 -TQEI-DPARDETKCAFWEYSPSMMGH-WSLDGCIRTRVNTTHTSCSCNHLTHFAILM---SSAR 462

  Fly   756 HSLFTMFDGNMRIFIYISIGICVVFIVIALLTLKLFNGVFVKSARTSIYTSIYLCLLAIELLFLL 820
            .:|...::...|| ..:.:.|.::.:.:.:.|...|..  :::.||:|:.::...|...:.:||:
Zfish   463 ANLLAHYNVLTRI-TQLGMVISLICLSMCIFTFWFFRD--IQNTRTTIHKNLCCSLFMAQFIFLI 524

  Fly   821 GIEQTETSIFCGFITIFLHCAILSGTAWFCYEAFHSYSTLTS---DELLLEVDQTPKVNCYYLLS 882
            ||.::....||..|...||...|:..||.|.|..|.|..:..   ::..|..:       :|...
Zfish   525 GINKSAHKWFCSLIAGLLHYFFLAAFAWMCIEGIHLYLIVVGVIYNKGFLHRN-------FYAFG 582

  Fly   883 YGLSLSVVAISLVIDPSTYTQNDYCVLMEANALFYATFVIP-VLVFFVAAIGYTFLSWIIMCRKS 946
            ||....|||||..:....|..:..|.|...|. |..:|:.| :|:..|..:.:..:.:.:.   .
Zfish   583 YGSPAVVVAISATLGYKYYGTSSVCWLSTENN-FIWSFIGPAILIILVNLLAFAVIIYKVY---R 643

  Fly   947 RTGLKTKEHTRLASVRFDIRCSFVFLLLLSAVWCSAYFYLRGAKMDDDTADVYGYCFICFNTLLG 1011
            .|.:|..|.:...::|...|.:...|.:|...|.....|:    :.:.|...|.:.|.  |...|
Zfish   644 HTAVKKPEISHYENIRSCARGAIALLFVLGVTWAFGVMYI----LYETTLTAYLFTFA--NVFQG 702

  Fly  1012 LYIFVFHCIQNEKIRREYRKYVRQHAWLPKCLRC 1045
            ::||:|.|:.:.:|:.||.:..:.   :|.|..|
Zfish   703 MFIFIFLCVLSRRIQEEYYRLFKN---MPCCFEC 733

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.