Protein Alignment Cirl and mthl2

DIOPT Version :9

• Sequence 1: NP_001260807.1
• Gene: Cirl / 35846
• FlyBaseID: FBgn0033313
• Length: 1711
• Species: Drosophila melanogaster
• Sequence 2: NP_788462.2
• Gene: mthl2 / 38636
• FlyBaseID: FBgn0035623
• Length: 518
• Species: Drosophila melanogaster
• Alignment Length: 402
• Identity: 76/402 - (18%)
• Similarity: 139/402 - (34%)
• Gaps: 127/402 - (31%)

  Fly   749 DVVDEH------------------------QHSLFTMFDGN---MRIF---------------IY 771
            |::||:                        ||..|.  :||   :||.               :.
  Fly   162 DIMDEYTLFENGRLLRHYDQVYLDKSEYCLQHRTFG--EGNNNSIRIIPHNCLILPSRTGQTVVM 224

  Fly   772 ISIGICVVF-IVIALLTLKLFN---GVFVKSARTSIYTSIYLCLLAIELLFLLGIEQTETSI-FC 831
            |:..||:|. |.:.|...||.|   ..|:          .|:..|....|||| ::..|.|: ||
  Fly   225 ITSLICLVLTIAVYLCVKKLMNLEGKCFI----------CYMMCLFFGYLFLL-LDLWELSLDFC 278

  Fly   832 ---GFITIFLHCAILSGTAWFCYEAFHSYSTLTSDELLLEVDQTPKVNCYYLLSYGLSLSVVAIS 893
               ||:..|.   :::...|....:.|.:..||:....:.:........|...::.:.|::..::
  Fly   279 KAAGFLGYFF---VMAAFFWLSIISRHYWKCLTNPCASMNIRSERAFLLYSCFAWAMPLALTGVT 340

  Fly   894 LVIDPSTYTQND--------------YCVLMEANALFYATFVIPVLVFFVAAIGYTFLSWIIMCR 944
            .:.|  ....|:              |.....|...||...|:  |:.|...:.......||..:
  Fly   341 YLAD--NVVNNEEWQPRVGDEGHCWIYTKSWSAMVYFYGPMVL--LILFNITMFVLTAKHIIDSK 401

  Fly   945 KSRTGLKTKEHTRLASVRFDIRCSFVFLLLLSAVWCSAYFYLRGAKMDDDTADVYGY-------- 1001
            ::...:...| .|:..:..|.:....||||.:.:..|..|            :::.|
  Fly   402 RTLRKIARNE-GRIQKLNSDKQNYTQFLLLFTVMGMSWSF------------EIFSYLVQREKLW 453

  Fly  1002 --CFIC---FNTLLGLYIFVFHCIQNEKIRREYRKYVRQHAWLPKCLRCSKTSISSGIVTGNGPT 1061
              .|:.   ||...|:.|||...::.:.:.. ::|.:     .||....|:::           |
  Fly   454 VNIFLVADYFNWSQGVIIFVLFILRRKTLVL-FKKQI-----FPKQRAFSRSA-----------T 501

  Fly  1062 AGTLCSVSTSKK 1073
            ..|:.|:|.:|:
  Fly   502 QSTIESISQTKR 513

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cirl	NP_001260807.1	Gal_Lectin	33..113	CDD:280328
		GAIN	453..680	CDD:293098
		GPS	705..752	CDD:197639	1/2 (50%)
		7tm_4	763..1014	CDD:304433	58/303 (19%)
mthl2	NP_788462.2	Methuselah_N	31..211	CDD:284145	10/50 (20%)
		7tm_4	221..>395	CDD:304433	38/191 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4193
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900