DRSC/TRiP Functional Genomics Resources

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Protein Alignment Cirl and Dh44-R2

DIOPT Version :10

Sequence 1:NP_001260807.1 Gene:Cirl / 35846 FlyBaseID:FBgn0033313 Length:1711 Species:Drosophila melanogaster
Sequence 2:NP_610789.3 Gene:Dh44-R2 / 36368 FlyBaseID:FBgn0033744 Length:476 Species:Drosophila melanogaster


Alignment Length:347 Identity:64/347 - (18%)
Similarity:136/347 - (39%) Gaps:75/347 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly   723 GCSLESTNRTHSVCSCN----HLTNFAILMDVVDE-HQHS----LFTMFDGNMRIFIYISIG--- 775
            |...::|:.....|..|    |.:::       |. ||:|    :...|..|:.:...|..|   
  Fly   113 GVHYDTTDNATRFCFPNGTWDHYSDY-------DRCHQNSGSIPVVPDFSPNVELPAIIYAGGYF 170

  Fly   776 ICVVFIVIALLTLKLFNGVFVKSARTSIYTSIYL-----CLLAIELLFLLGIEQTETSIFCGFIT 835
            :....:|:||:....|..  ::..|.:|:.:::|     .||.|..|||..|....:...|..:.
  Fly   171 LSFATLVVALIIFLSFKD--LRCLRNTIHANLFLTYITSALLWILTLFLQVITTESSQAGCITLV 233

  Fly   836 IFLHCAILSGTAWFCYEAFHSYS----TLTSDELLLEVDQTPKVNCYYLLSYG---LSLSVVAIS 893
            |......|:...|...|..:.|:    |.:||.:...:        |.|:.:|   :.:.|.:|:
  Fly   234 IMFQYFYLTNFFWMFVEGLYLYTLVVQTFSSDNISFII--------YALIGWGCPAVCILVWSIA 290

  Fly   894 LVIDPSTYTQNDY-------CVLMEANALFYATFVIPV-------LVFFVAAIGYTFLSWIIMCR 944
            ....|  :.:|::       |..|..:.:.: .|.:|.       |||.:.      :.|:::.:
  Fly   291 KAFAP--HLENEHFNGLEIDCAWMRESHIDW-IFKVPASLALLVNLVFLIR------IMWVLITK 346

  Fly   945 -KSRTGLKTKEHTRLASVRFDIRCSFVFLLLLSAVWCSAYFYLRGAKMDDDTADVYGYCFICFNT 1008
             :|...|:|:::.:.:..          ||:|..::...|..:........:.:::........:
  Fly   347 LRSAHTLETRQYYKASKA----------LLVLIPLFGITYLLVLTGPEQGISRNLFEAIRAFLIS 401

  Fly  1009 LLGLYIFVFHCIQNEKIRREYR 1030
            ..|.::.:|:|..|.::|:..|
  Fly   402 TQGFFVALFYCFLNSEVRQTLR 423

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CirlNP_001260807.1 Gal_Rha_Lectin_dCirl 22..113 CDD:438687
GAIN 451..682 CDD:465137
GPS 705..752 CDD:197639 5/32 (16%)
7tmB2_CELSR_Adhesion_IV 763..1035 CDD:320557 54/298 (18%)
TM helix 1 765..790 CDD:320557 6/27 (22%)
TM helix 2 801..823 CDD:320557 8/26 (31%)
TM helix 3 832..859 CDD:320557 5/30 (17%)
TM helix 4 875..895 CDD:320557 5/22 (23%)
TM helix 5 913..942 CDD:320557 6/35 (17%)
TM helix 6 960..987 CDD:320557 4/26 (15%)
TM helix 7 997..1022 CDD:320557 3/24 (13%)
Herpes_TAF50 <1219..1365 CDD:308764
Dh44-R2NP_610789.3 HRM 82..144 CDD:397086 7/37 (19%)
7tmB1_DH_R 158..428 CDD:320391 53/295 (18%)
TM helix 1 160..185 CDD:320391 5/24 (21%)
TM helix 2 194..216 CDD:320391 5/21 (24%)
TM helix 3 230..257 CDD:320391 5/26 (19%)
TM helix 4 269..289 CDD:320391 4/27 (15%)
TM helix 5 314..343 CDD:320391 6/35 (17%)
TM helix 6 357..384 CDD:320391 4/36 (11%)
TM helix 7 390..415 CDD:320391 3/24 (13%)
Blue background indicates that the domain is not in the aligned region.

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