DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cirl and Dh44-R2

DIOPT Version :9

Sequence 1:	NP_001260807.1	Gene:	Cirl / 35846	FlyBaseID:	FBgn0033313	Length:	1711	Species:	Drosophila melanogaster
Sequence 2:	NP_610789.3	Gene:	Dh44-R2 / 36368	FlyBaseID:	FBgn0033744	Length:	476	Species:	Drosophila melanogaster

Alignment Length:	347	Identity:	64/347 - (18%)
Similarity:	136/347 - (39%)	Gaps:	75/347 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   723 GCSLESTNRTHSVCSCN----HLTNFAILMDVVDE-HQHS----LFTMFDGNMRIFIYISIG--- 775
            |...::|:.....|..|    |.:::       |. ||:|    :...|..|:.:...|..|
  Fly   113 GVHYDTTDNATRFCFPNGTWDHYSDY-------DRCHQNSGSIPVVPDFSPNVELPAIIYAGGYF 170

  Fly   776 ICVVFIVIALLTLKLFNGVFVKSARTSIYTSIYL-----CLLAIELLFLLGIEQTETSIFCGFIT 835
            :....:|:||:....|..  ::..|.:|:.:::|     .||.|..|||..|....:...|..:.
  Fly   171 LSFATLVVALIIFLSFKD--LRCLRNTIHANLFLTYITSALLWILTLFLQVITTESSQAGCITLV 233

  Fly   836 IFLHCAILSGTAWFCYEAFHSYS----TLTSDELLLEVDQTPKVNCYYLLSYG---LSLSVVAIS 893
            |......|:...|...|..:.|:    |.:||.:...:        |.|:.:|   :.:.|.:|:
  Fly   234 IMFQYFYLTNFFWMFVEGLYLYTLVVQTFSSDNISFII--------YALIGWGCPAVCILVWSIA 290

  Fly   894 LVIDPSTYTQNDY-------CVLMEANALFYATFVIPV-------LVFFVAAIGYTFLSWIIMCR 944
            ....|  :.:|::       |..|..:.:.: .|.:|.       |||.:.      :.|:::.:
  Fly   291 KAFAP--HLENEHFNGLEIDCAWMRESHIDW-IFKVPASLALLVNLVFLIR------IMWVLITK 346

  Fly   945 -KSRTGLKTKEHTRLASVRFDIRCSFVFLLLLSAVWCSAYFYLRGAKMDDDTADVYGYCFICFNT 1008
             :|...|:|:::.:.:..          ||:|..::...|..:........:.:::........:
  Fly   347 LRSAHTLETRQYYKASKA----------LLVLIPLFGITYLLVLTGPEQGISRNLFEAIRAFLIS 401

  Fly  1009 LLGLYIFVFHCIQNEKIRREYR 1030
            ..|.::.:|:|..|.::|:..|
  Fly   402 TQGFFVALFYCFLNSEVRQTLR 423

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cirl	NP_001260807.1	Gal_Lectin	33..113	CDD:280328
		GAIN	453..680	CDD:293098
		GPS	705..752	CDD:197639	5/32 (16%)
		7tm_4	763..1014	CDD:304433	49/280 (18%)
Dh44-R2	NP_610789.3	HRM	82..144	CDD:280888	7/37 (19%)
Dh44-R2	NP_610789.3	7tm_2	159..407	CDD:278432	48/276 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462222
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840