DRSC/TRiP Functional Genomics Resources

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Protein Alignment Cirl and Adgrg5

DIOPT Version :9

Sequence 1:NP_001260807.1 Gene:Cirl / 35846 FlyBaseID:FBgn0033313 Length:1711 Species:Drosophila melanogaster
Sequence 2:XP_008770523.1 Gene:Adgrg5 / 307645 RGDID:1305559 Length:564 Species:Rattus norvegicus


Alignment Length:333 Identity:88/333 - (26%)
Similarity:136/333 - (40%) Gaps:78/333 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly   564 VQKVKNILLSVR------VLETKTIQSSVVFPDSDQWP---LSSDRI----------------EL 603
            :..::.:||:..      .|:|.:|| |:||..|..:|   |||..:                ||
  Rat    49 IHHLEQMLLNASFHGHNLTLQTNSIQ-SLVFKLSCGFPGLSLSSATLTNVSQAWAPHAMQFPAEL 112

  Fly   604 PRAALIDNSEGGLVRIVFAAFDRLESILKPSYDHFDLKSSRSYVRNTAILSNDSDVNAGEIQQRL 668
            .:.|.: .|....:|::...|                        .||.|..| |.|:.      
  Rat   113 TKNACV-TSRPAELRLICVYF------------------------FTAHLFQD-DRNSS------ 145

  Fly   669 RILNSKVISASLGKGRHIQLSQPITLTLKHLKTENVTNPTCVFW-----NYIDHAWSANGCSLES 728
             :||:.|:.|.|.......|.:|:.::..|.::......|||||     .:...|||..||..|.
  Rat   146 -LLNNYVLGAQLDHRPVNNLQRPVNISFWHNRSLEGYTVTCVFWKEGAGKHSWGAWSPKGCYTEQ 209

  Fly   729 TNRTHSVCSCNHLTNFAILMDVV-DEHQHSLFTMFDGNMRIFIYISIGICVVFIVIALLTLKLFN 792
            .:.|..:|.|||||.||:||.:. |.....|.|..:       |||:..|.:.||.:|||: |.|
  Rat   210 PSPTQVLCHCNHLTYFAVLMQLSGDPVPTELQTPLE-------YISLVGCSISIVASLLTI-LLN 266

  Fly   793 GVFVK--SARTSIYTSIYLCLLAIELLFLLGIEQTETSI---FCGFITIFLHCAILSGTAWFCYE 852
            ....|  .:.|.|:.::...:|.:.:.|||..:....::   .|..:...||.|:||...|...|
  Rat   267 AHSRKLSDSTTRIHLNLNGSVLLLNITFLLSSQMVPPTVPRSVCTVLAATLHYALLSSLTWMGVE 331

  Fly   853 AFHSYSTL 860
            .|:.|..|
  Rat   332 GFNLYLLL 339

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CirlNP_001260807.1 Gal_Lectin 33..113 CDD:280328
GAIN 453..680 CDD:293098 30/140 (21%)
GPS 705..752 CDD:197639 22/52 (42%)
7tm_4 763..1014 CDD:304433 29/103 (28%)
Adgrg5XP_008770523.1 GPS 184..228 CDD:396408 20/43 (47%)
7tm_GPCRs 243..>349 CDD:421689 29/105 (28%)
TM helix 1 243..268 CDD:410628 11/32 (34%)
TM helix 2 277..299 CDD:410628 6/21 (29%)
TM helix 3 311..338 CDD:410628 9/26 (35%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG4193
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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