Protein Alignment CG8642 and angptl2a

DIOPT Version :9

• Sequence 1: NP_610396.2
• Gene: CG8642 / 35845
• FlyBaseID: FBgn0033312
• Length: 429
• Species: Drosophila melanogaster
• Sequence 2: NP_001025401.1
• Gene: angptl2a / 569092
• ZFINID: ZDB-GENE-080721-15
• Length: 525
• Species: Danio rerio
• Alignment Length: 474
• Identity: 122/474 - (25%)
• Similarity: 215/474 - (45%)
• Gaps: 104/474 - (21%)

  Fly    35 EIPPTNGTQIGNVTAVAP-------------VPEKLAEVHIDQHKTIRISKGD----------LD 76
            |.|.|:.|...:.|.:.|             .||.|.|..:::.: :.:..|:          |.
Zfish    54 EPPSTSDTDKCSYTFIVPQRKSTGAICVNSKEPEALLENRVNKQE-LELLNGELHKQRRQIETLQ 117

  Fly    77 DLLDVYMGKIAESAATIKDKEN-EINKLQTKDQTGDELLRKFENLTQVCSAQQS--SFTTAIKEK 138
            .|::|..|.:.|.....|:..| .....|...|...|::||.:|..:|...:..  :.|:.:::.
Zfish   118 QLVEVDGGVVNEVKLLRKESRNMNARVTQLYMQLLHEIIRKRDNALEVSQLENRVLNHTSEMQQL 182

  Fly   139 DEQIKELEQKVKVYETRLKRKQHVLAELRKLNGSSALL--------------------------- 176
            ..:.::||.|.:...:....:..|:.:|.:.......:
Zfish   183 TSRYRDLEHKYQHLASLASNQSAVIVQLEEQCRRGGFVGGRQTRPYQPPVVPPQPAQTPQHRQPP 247

  Fly   177 ---IEHLKGKVVY---FERKFREKKDDLLADWEA-ATTSCVPFGRSP--GIHLIHLPGFLPFLVP 232
               :.|...:..:   :.|:..:..:::.:|..: |..|.:|..:|.  ......|.|  || ..
Zfish   248 PPPVHHSPARPFHPPTYPRQNNQMTNEIQSDQNSKAMPSALPTEQSETHSFSTDKLSG--PF-KD 309

  Fly   233 C-----EGQTAAG-----------------------PGWTCIQRRLDGSVNFYRNWDAYSKGFGK 269
            |     ||.:.:|                       .|||.||||:||||||:|||:.|.:|||.
Zfish   310 CLQALEEGHSNSGMFLLKPENTNKLMQVWCDQRHDPGGWTVIQRRMDGSVNFFRNWETYKQGFGN 374

  Fly   270 LNGEFFIGLEKLHRLTSSQPHELYISIRRFGGETSYAHYDDFLIGSEEEGYELKLLGHYQGNASD 334
            ::||:::|||.::.||:...::|.:::..:.|..::|.|..|.:..|.:.|::: :|.|.|||.|
Zfish   375 IDGEYWLGLENIYWLTNQGNYKLLVTLEDWSGRKTFAEYASFRLEPEADFYKMR-VGRYHGNAGD 438

  Fly   335 ALRTHDKMKFSTYDRDNDAFTHMNCAEHHQGAWWYDFCSRSNLNGRYFKGEVDNPQSIYWEP--W 397
            ::..|:..:|:|.|||:||:|. |||.:.:|.|||:.|:.|||||.:::|  .:.:|.|.:.  |
Zfish   439 SMTWHNGKQFTTLDRDHDAYTG-NCAHYQKGGWWYNACAHSNLNGVWYRG--GHYRSRYQDGVYW 500

  Fly   398 YSFR----SLKSVQMLIRP 412
            ..||    |||.|.|:|||
Zfish   501 AEFRGGSYSLKKVTMMIRP 519

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8642	NP_610396.2	GluZincin	72..>163	CDD:301352	19/103 (18%)
		FReD	213..413	CDD:238040	85/236 (36%)
angptl2a	NP_001025401.1	DUF1875	<50..>147	CDD:286100	18/93 (19%)
		Fib_alpha	119..215	CDD:285864	19/95 (20%)
		FReD	305..519	CDD:238040	81/220 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2579
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm25543
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X25
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.810