Protein Alignment CG8642 and ANGPTL4

DIOPT Version :9

• Sequence 1: NP_610396.2
• Gene: CG8642 / 35845
• FlyBaseID: FBgn0033312
• Length: 429
• Species: Drosophila melanogaster
• Sequence 2: XP_005272541.1
• Gene: ANGPTL4 / 51129
• HGNCID: 16039
• Length: 424
• Species: Homo sapiens
• Alignment Length: 445
• Identity: 118/445 - (26%)
• Similarity: 187/445 - (42%)
• Gaps: 102/445 - (22%)

  Fly    38 PTNGTQIGNVTAVA--------PVPEKLA------EVHIDQHKTIRISKGDLDDLLDVYMGKIAE 88
            ||.|..:....|.|        ||..|..      |:::..|..:::.:|            :.|
Human     5 PTAGAALMLCAATAVLLSAQGGPVQSKSPRFASWDEMNVLAHGLLQLGQG------------LRE 57

  Fly    89 SAATIKDKENEINKLQTKDQTGDELLRKFENLTQVCSAQQS--------SFTTAIKEKDEQIKEL 145
            .|...:   ::::.|:.:........:..|..|.:..|.:|        |..|.:|.::.:|::|
Human    58 HAERTR---SQLSALERRLSACGSACQGTEGSTDLPLAPESRVDPEVLHSLQTQLKAQNSRIQQL 119

  Fly   146 EQKVKVYETRLKRKQHVLAELRKLNGSSALLIEHLKGKVVYFERKF----------REKKDDLLA 200
            ..||...:..|: |||             |.|:||:.:....:.|.          |::..::..
Human   120 FHKVAQQQRHLE-KQH-------------LRIQHLQSQFGLLDHKHLDHEVAKPARRKRLPEMAQ 170

  Fly   201 DWEAA---------TTSCVPF----GRSPGIHLIHLPGFLPFLVPCEGQTAAGPGWTCIQRRLDG 252
            ..:.|         ...|...    .|..|:..|...|..||||.|: .|:.| |||.||||.||
Human   171 PVDPAHNVSRLHRLPRDCQELFQVGERQSGLFEIQPQGSPPFLVNCK-MTSDG-GWTVIQRRHDG 233

  Fly   253 SVNFYRNWDAYSKGFGKLNGEFFIGLEKLHRLTSSQPHELYISIRRFGGETSYAHYDDFLIGSEE 317
            ||:|.|.|:||..|||..:|||::||||:|.:|..:...|.:.:|.:.|......:...| |.|:
Human   234 SVDFNRPWEAYKAGFGDPHGEFWLGLEKVHSITGDRNSRLAVQLRDWDGNAELLQFSVHL-GGED 297

  Fly   318 EGYELKLLGHYQG--NASDALRTHDKMKFSTYDRDNDAFTHMNCA------------EH------ 362
            ..|.|:|.....|  .|:....:...:.|||:|:|:|.....|||            :|
Human   298 TAYSLQLTAPVAGQLGATTVPPSGLSVPFSTWDQDHDLRRDKNCAKSLSAPSVAQRPDHVPSPLT 362

  Fly   363 HQGAWWYDFCSRSNLNGRYFKGEVDNPQ----SIYWEPWYS-FRSLKSVQMLIRP 412
            ..|.||:..||.|||||:||:......|    .|:|:.|.. :..|::..|||:|
Human   363 PAGGWWFGTCSHSNLNGQYFRSIPQQRQKLKKGIFWKTWRGRYYPLQATTMLIQP 417

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8642	NP_610396.2	GluZincin	72..>163	CDD:301352	19/98 (19%)
		FReD	213..413	CDD:238040	81/225 (36%)
ANGPTL4	XP_005272541.1	FReD	183..418	CDD:238040	82/238 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2579
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810