Protein Alignment CG8642 and Angptl3

DIOPT Version :9

• Sequence 1: NP_610396.2
• Gene: CG8642 / 35845
• FlyBaseID: FBgn0033312
• Length: 429
• Species: Drosophila melanogaster
• Sequence 2: XP_006238502.1
• Gene: Angptl3 / 502970
• RGDID: 1564505
• Length: 455
• Species: Rattus norvegicus
• Alignment Length: 477
• Identity: 125/477 - (26%)
• Similarity: 212/477 - (44%)
• Gaps: 93/477 - (19%)

  Fly     4 YSIILILIMLPSAWCLQVPSKIKSTTKAPVKEIPPTNGTQIGNVTAVAPVPEKLAEVHIDQHKTI 68
            ::|.|:|.::|    |.:.|:: ....:|...:|....::...:..|..:...|.::.......:
  Rat     2 HTIKLLLFVVP----LVISSRV-DPDLSPFDSVPSEPKSRFAMLDDVKILANGLLQLGHGLKDFV 61

  Fly    69 RISKGDLDD------LLDVYMGKIAESAATIKDKENEI----NKLQTKDQ----TGDELLRKFEN 119
            ..:||.::|      :.|.....::.....||::|.|:    :|||.|::    ...||..|.|:
  Rat    62 HKTKGQINDIFQKLNIFDQCFYDLSLQTNEIKEEEKELRRTTSKLQVKNEEVKNMSLELNSKLES 126

  Fly   120 LTQVCSAQQ--------------------------SSFTTAIKEKDEQIKELEQKVKVYETRLKR 158
            |.:...|.|                          :|..:.::::|..|:||.|.|:....:|.
  Rat   127 LLEEKMALQHRVRALEEQLTSLVQNPPGAREHPEVTSLKSFVEQQDNSIRELLQSVEEQYKQLS- 190

  Fly   159 KQHVLA-----ELRKLN----GSSALLIE----------HLKGKVVYFERKFREKKDDLLADWEA 204
            :||:..     :|||..    ..::|..:          |||      |.|..| :|||.||..|
  Rat   191 QQHIQIKEIENQLRKTGIQEPTENSLYSKPRAPRTTPPLHLK------EAKNIE-QDDLPADCSA 248

  Fly   205 ATTSCVPFGR---SPGIHLIHLPGFLPFLVPCEGQTAAGPGWTCIQRRLDGSVNFYRNWDAYSKG 266
            .      :.|   :.|::.|.......|.|.|:  |.:|...|.||.|.|||.||.:.|:.|.||
  Rat   249 I------YNRGEHTSGVYTIRPSSSQVFNVYCD--TQSGTPRTLIQHRKDGSQNFNQTWENYEKG 305

  Fly   267 FGKLNGEFFIGLEKLHRLTSSQPHELYISIRRFGGETSYAHYDDFLIGSEEEGYELKLLGHYQGN 331
            ||:|:|||::||||::.:.....:.|.:.::.:.....||.| .|.:|:.|..|.|. :.....|
  Rat   306 FGRLDGEFWLGLEKIYAIVKQSNYILRLELQDWKDSKHYAEY-SFHLGNHETNYTLH-VAEIAAN 368

  Fly   332 ASDALRTHDKMKFSTYDRDNDAFTHMNCAEHHQGAWWY-DFCSRSNLNGRY----FKGEVDNPQS 391
            ..:||..|..:.|||:  |:.|...:.|.|.:.|.||: |.|..:||||:|    .|.:.:..:.
  Rat   369 IPEALPEHRDLMFSTW--DHRAKGQLYCPESYSGGWWFSDMCGENNLNGKYNKPRAKSKPERRRG 431

  Fly   392 IYWEP-WYSFRSLKSVQMLIRP 412
            |.|.| .....|:||.:|:::|
  Rat   432 ISWRPRGGKLYSIKSSKMMLQP 453

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8642	NP_610396.2	GluZincin	72..>163	CDD:301352	29/130 (22%)
		FReD	213..413	CDD:238040	70/209 (33%)
Angptl3	XP_006238502.1	SPEC	<34..193	CDD:295325	29/159 (18%)
		FReD	241..453	CDD:238040	74/223 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2579
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810