DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8642 and angptl7

DIOPT Version :9

Sequence 1:	NP_610396.2	Gene:	CG8642 / 35845	FlyBaseID:	FBgn0033312	Length:	429	Species:	Drosophila melanogaster
Sequence 2:	NP_001006073.1	Gene:	angptl7 / 450053	ZFINID:	ZDB-GENE-041010-175	Length:	338	Species:	Danio rerio

Alignment Length:	415	Identity:	111/415 - (26%)
Similarity:	183/415 - (44%)	Gaps:	89/415 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 SIILILIMLPSAWCLQVPSKIKSTTKAPVKEIPPTNGTQIGNVTAVAPVPEKLAEVHIDQHKTIR 69
            |:.|:|::|..|....|..|..:|.|       |..|.|.                 .|:.::::
Zfish     5 SLTLLLLVLGHAMAQNVLKKNLATPK-------PVKGAQC-----------------CDEVRSLK 45

  Fly    70 ISKGDLDDLLDVYMGKIAESAATIKDKENEINKLQTKDQTGDELLRKFENLTQVCSAQQSSFTTA 134
            :...:|..:|:                  |:||.|.     .||::....:.::....|
Zfish    46 VQVANLSSMLE------------------ELNKKQE-----SELMKVVRQMMELEKLNQ------ 81

  Fly   135 IKEKDEQIKELEQKVKVYETRLKRKQHVLAELRKLNGSSALLIE--HLKGKVVYFERKFREKKDD 197
              :::.::.|.|.|......:::..|...|:......:|..:.:  .|..|......:::..|||
Zfish    82 --QQEARVTEAESKYSEIYNQIEIMQLQAAQSAPQQSTSDAIYDCASLYNKNYKISGEYKLPKDD 144

  Fly   198 LLADWEAATTSCVPFGRSPGIHLIHLPGFLPFLVPCEGQTAAGPGWTCIQRRLDGSVNFYRNWDA 262
            .|.              :|.:::.           |:.:...| |||.||||..|..:|.|:|..
Zfish   145 FLG--------------TPELNVF-----------CDMENNGG-GWTLIQRRKIGLTSFNRDWKQ 183

  Fly   263 YSKGFGKLNGEFFIGLEKLHRLTSSQPHELYISIRRFGGETSYAHYDDFLIGSEEEGYELKLLGH 327
            |..|||.:.|:|::|.|.:.|:| .||..|.|.:..:.|:..||.|..|.:.:|...|:| |:.:
Zfish   184 YKNGFGTIRGDFWLGNEHIFRMT-RQPTVLRIEMEDWEGDVRYAEYGFFTLSNEMNSYKL-LIAN 246

  Fly   328 YQGNASDALRTHDKMKFSTYDRDNDAFTHMNCAEHHQGAWWYDFCSRSNLNGRYFK--GEVDNPQ 390
            |.|||.|:||.|:...|||.::|||.... |||:..||.:||:.|:.|||||.:::  ....||.
Zfish   247 YSGNAGDSLRYHNNTNFSTKNKDNDKCLD-NCAQLRQGGYWYNCCTDSNLNGVFYRYGSHTKNPD 310

  Fly   391 SIYWEPWYSFR-SLKSVQMLIRPKS 414
            .|.|..|:... |||.|:|.|||::
Zfish   311 GISWYGWHGPNYSLKRVEMKIRPQT 335

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8642	NP_610396.2	GluZincin	72..>163	CDD:301352	13/90 (14%)
CG8642	NP_610396.2	FReD	213..413	CDD:238040	76/202 (38%)
angptl7	NP_001006073.1	FReD	122..333	CDD:238040	81/239 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2579
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3359
SonicParanoid	1	1.000	-	-		X25
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.840