DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8642 and mfap4.1

DIOPT Version :9

Sequence 1:	NP_610396.2	Gene:	CG8642 / 35845	FlyBaseID:	FBgn0033312	Length:	429	Species:	Drosophila melanogaster
Sequence 2:	NP_001315274.1	Gene:	mfap4.1 / 405825	ZFINID:	ZDB-GENE-040426-2246	Length:	242	Species:	Danio rerio

Alignment Length:	238	Identity:	87/238 - (36%)
Similarity:	129/238 - (54%)	Gaps:	18/238 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   198 LLADWEAATTSCVPFGRS---------PGIHLIHLPGFLPFLVPC----EGQTAAGPGWTCIQRR 249
            ||:...|:..:.:||..|         .|::.|:..|..|..|.|    :|:.....|||.||||
Zfish    10 LLSAALASDCTSMPFDCSDIYKSGETLSGVYTIYPAGETPVWVYCQMLSDGKDEENGGWTVIQRR 74

  Fly   250 LDGSVNFYRNWDAYSKGFGKLNGEFFIGLEKLHRLTSSQPHELYISIRRFGGETSYAHYDDFLIG 314
            :||||||||.|..|.:|||.:.||:::|||.|::||..:...|.:.:..|.|...:|.|..|.:|
Zfish    75 MDGSVNFYRPWRDYKRGFGNVEGEYWLGLENLYQLTRHKKFMLRVDLEDFEGRRGFAQYSSFSVG 139

  Fly   315 SEEEGYELKLLGHYQGNASDALRTHDKMKFSTYDRDNDAFTHMNCAEHHQGAWWYDFCSRSNLNG 379
            .|.|||:|::.|...|.|.|:|..|:.:||||:|:|.|.: ..|||:...||:||..|..:|.|.
Zfish   140 CECEGYKLQVSGFTDGGAGDSLSGHNGVKFSTFDKDQDTY-DKNCAKEFLGAFWYGSCHTTNPNA 203

  Fly   380 RYFKGEVDNPQSIYWEPWYSFRSLKSVQMLIRPKSQLELKDLP 422
            .|..|| |.........||:::...:|.|.|   ..:::|.:|
Zfish   204 VYLWGE-DATHHAIGVCWYTWKGTHTVSMKI---ISMKIKQMP 242

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8642	NP_610396.2	GluZincin	72..>163	CDD:301352
CG8642	NP_610396.2	FReD	213..413	CDD:238040	80/212 (38%)
mfap4.1	NP_001315274.1	FReD	23..239	CDD:238040	82/220 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2579
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000029
OrthoInspector	1	1.000	-	-		mtm6504
orthoMCL	1	0.900	-	-		OOG6_100073
Panther	1	1.100	-	-	O	PTHR19143
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X25
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.810