DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8642 and sca

DIOPT Version :9

Sequence 1:	NP_610396.2	Gene:	CG8642 / 35845	FlyBaseID:	FBgn0033312	Length:	429	Species:	Drosophila melanogaster
Sequence 2:	NP_476710.2	Gene:	sca / 36411	FlyBaseID:	FBgn0003326	Length:	799	Species:	Drosophila melanogaster

Alignment Length:	416	Identity:	109/416 - (26%)
Similarity:	184/416 - (44%)	Gaps:	90/416 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    53 VPEKLAEVHIDQHKTIRISKGDLD----------------DLLDVYMGKIAESAATIKDKENEIN 101
            :.|::..:.::||   ||:..:.:                :||:...|...:...:|.:..:||:
  Fly   352 IDERVRSIEVEQH---RIANANFNLSSQIASLDKLHTSMLELLEDVEGLQTKMDKSIPELRHEIS 413

  Fly   102 KLQTKDQ--TGDELLRKFENLTQVCSAQQSSFTTAI-KEKDEQIKELEQKVKVYETRLKRKQHVL 163
            ||:..:.  |.::.|.:.|......|.|..:.:.:: :|:.|.:::|...|....|.:.|.|
  Fly   414 KLEFANAQITSEQSLIREEGTNAARSLQAMAVSVSVLQEEREGMRKLSANVDQLRTNVDRLQ--- 475

  Fly   164 AELRKLNGSSALLIEHLKGKVVYFERKFRE----------KKDD----------LLADWEAATT- 207
                      :|:.:.:|.|:.:..:..:.          .:||          |:::.|...|
  Fly   476 ----------SLVNDEMKNKLTHLNKPHKRPHHQNVQAQMPQDDSPIDSVLAETLVSELENVETQ 530

  Fly   208 -----SCVPFG------RSPGIHLIHLPGFL-PFLVPCEGQTAAGPGWTCIQRRLDGSVNFYRNW 260
                 :.:|..      ::.|:|||...|.. |.:..|     ...|||.:|||.|||.:|.|:|
  Fly   531 YEAIINKLPHDCSEVHTQTDGLHLIAPAGQRHPLMTHC-----TADGWTTVQRRFDGSADFNRSW 590

  Fly   261 DAYSKGFGKLNGEFFIGLEKLHRLTSSQPHELYISIRRFGGETSYAHYDDFLIGSEEEGYELKLL 325
            ..|::|||...|||:||.|:||.||......|.:.::........|.|..|.|.|..:||.|. :
  Fly   591 ADYAQGFGAPGGEFWIGNEQLHHLTLDNCSRLQVQMQDIYDNVWVAEYKRFYISSRADGYRLH-I 654

  Fly   326 GHYQGNASDALRTHDKMKFSTYDRDNDAFTHMNCAEHHQGAWWYDFCSRSNLNGRYFKGEVDNPQ 390
            ..|.|||||||.....|:||..|.|.| .:..:||.:::|.||:..|..:||||||..|
  Fly   655 AEYSGNASDALNYQQGMQFSAIDDDRD-ISQTHCAANYEGGWWFSHCQHANLNGRYNLG------ 712

  Fly   391 SIYW-----EPWYSFRSLKSVQMLIR 411
             :.|     ..|.   ::||.:||::
  Fly   713 -LTWFDAARNEWI---AVKSSRMLVK 734

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8642	NP_610396.2	GluZincin	72..>163	CDD:301352	20/109 (18%)
CG8642	NP_610396.2	FReD	213..413	CDD:238040	75/211 (36%)
sca	NP_476710.2	PRK13923	<200..300	CDD:276343
sca	NP_476710.2	FBG	538..736	CDD:214548	76/214 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2579
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm14151
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR19143
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.910