DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8642 and tnn

DIOPT Version :9

Sequence 1:	NP_610396.2	Gene:	CG8642 / 35845	FlyBaseID:	FBgn0033312	Length:	429	Species:	Drosophila melanogaster
Sequence 2:	XP_005171321.1	Gene:	tnn / 30234	ZFINID:	ZDB-GENE-990415-262	Length:	1020	Species:	Danio rerio

Alignment Length:	187	Identity:	78/187 - (41%)
Similarity:	108/187 - (57%)	Gaps:	14/187 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   231 VPCEGQTAAGPGWTCIQRRLDGSVNFYRNWDAYSKGFGKLNGEFFIGLEKLHRLTSSQPHELYIS 295
            |.|:.:|..| ||...|||..|.|:|.:.|..|.||||:|..||::||:|:|.||:: |.:..
Zfish   825 VYCDMKTDGG-GWIVFQRRNTGKVDFMKKWRDYMKGFGELTEEFWLGLDKIHELTNT-PTQYE-- 885

  Fly   296 IRRF----GGETSYAHYDDFLIGSEEEGYELKLLGHYQGNASDALRTHDKMKFSTYDRDNDAFTH 356
             .||    |.:..||.||:|.:...::.::| .:|.|:|||.||:..|....|||.|.||| ...
Zfish   886 -ARFDLGSGSDRKYAVYDNFKVAPSKQKFKL-TIGSYKGNAGDAMTYHQGAPFSTVDSDND-IAL 947

  Fly   357 MNCAEHHQGAWWYDFCSRSNLNGRYFKGEVDNPQSIYWEPWYS-FRSLKSVQMLIRP 412
            .|||..|||||||..|..:|||||:  |:..:...:.||||.. .:||...::.|||
Zfish   948 GNCALTHQGAWWYKNCHLANLNGRF--GDNRHSMGVNWEPWKGHLQSLDFAEIKIRP 1002

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8642	NP_610396.2	GluZincin	72..>163	CDD:301352
CG8642	NP_610396.2	FReD	213..413	CDD:238040	78/187 (42%)
tnn	XP_005171321.1	EGF_alliinase	<133..163	CDD:282688
		EGF_2	161..189	CDD:285248
		EGF_2	193..220	CDD:285248
		EGF_2	224..251	CDD:285248
		fn3	257..333	CDD:278470
		fn3	344..426	CDD:278470
		fn3	435..514	CDD:278470
		fn3	523..602	CDD:278470
		fn3	611..683	CDD:278470
		fn3	699..773	CDD:278470
		FReD	792..1003	CDD:238040	78/187 (42%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2579
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100073
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.710