DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8642 and CG30281

DIOPT Version :9

Sequence 1:	NP_610396.2	Gene:	CG8642 / 35845	FlyBaseID:	FBgn0033312	Length:	429	Species:	Drosophila melanogaster
Sequence 2:	NP_726164.1	Gene:	CG30281 / 246525	FlyBaseID:	FBgn0050281	Length:	291	Species:	Drosophila melanogaster

Alignment Length:	251	Identity:	112/251 - (44%)
Similarity:	155/251 - (61%)	Gaps:	12/251 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly   176 LIEHLKGKVVYFERKFREKKDDLLADWEAATTSCVPFG-RSPGIHLIHLPGFLPFLVPCEGQTAA 239
            ::..||.::...::.::|..::..:......:||:..| .|.|||:|.:||..||.|.|:.: .|
  Fly    35 MVSSLKIRLEELKQSYKEITEERGSHETINPSSCLAAGINSNGIHVIEVPGLEPFPVYCDTR-LA 98

  Fly   240 GPGWTCIQRRLDGSVNFYRNWDAYSKGFGKLNGEFFIGLEKLHRLTSSQPHELYISIRRFGGETS 304
            |.|||.||||.|||.||||.|:.||:|||:|:||||:||||||.||:::|:||::.:..|.|...
  Fly    99 GSGWTVIQRRQDGSENFYRCWEEYSQGFGELSGEFFMGLEKLHFLTTAEPYELFVYMEDFNGVVH 163

  Fly   305 YAHYDDFLIGSEEEGYELKLLGHYQGNASDALRTHDKMKFSTYDRDNDAFTHMNCAEHHQGAWWY 369
            .|.|:||.||:....|.|.:||.|.|:|.|:||.|..|.|||:|.|:   |...||..:.|||||
  Fly   164 DARYEDFAIGNASASYALSVLGKYSGDAGDSLRYHKGMPFSTFDHDD---TGHGCARIYVGAWWY 225

  Fly   370 DFCSRSNLNGRYFKGEVDNP----QSIYWEPW--YSFRSLKSVQMLIRPKSQLELK 419
            |.|.||||||:|.:|....|    :.|.|..|  |.: ..|.|||:||||....|:
  Fly   226 DQCQRSNLNGQYLEGGRFEPKMSGRGITWMSWRGYDY-GYKFVQMMIRPKCSNNLR 280

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8642	NP_610396.2	GluZincin	72..>163	CDD:301352
CG8642	NP_610396.2	FReD	213..413	CDD:238040	104/206 (50%)
CG30281	NP_726164.1	FReD	63..274	CDD:238040	106/215 (49%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	187	1.000	Domainoid score	I3330
eggNOG	1	0.900	-	-		E1_KOG2579
Homologene	1	1.000	-	-		H122246
Inparanoid	1	1.050	91	1.000	Inparanoid score	I3666
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D49112at7147
OrthoFinder	1	1.000	-	-		FOG0000029
OrthoInspector	1	1.000	-	-		mtm6504
orthoMCL	1	0.900	-	-		OOG6_100073
Panther	1	1.100	-	-	P	PTHR19143
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X25
	11	10.870