Protein Alignment CG8642 and FGB

DIOPT Version :9

• Sequence 1: NP_610396.2
• Gene: CG8642 / 35845
• FlyBaseID: FBgn0033312
• Length: 429
• Species: Drosophila melanogaster
• Sequence 2: NP_005132.2
• Gene: FGB / 2244
• HGNCID: 3662
• Length: 491
• Species: Homo sapiens
• Alignment Length: 465
• Identity: 123/465 - (26%)
• Similarity: 191/465 - (41%)
• Gaps: 127/465 - (27%)

  Fly    22 PSKIKSTTKAPVKEIPPTNG-----TQIGNVTAVAPVPEKLAEVHIDQHKTIRISKGDLDDLLDV 81
            |:|..:|.|...::.|...|     ..:|   .:.|...:|.|..:.|.:.||.|..:|::
Human    75 PAKAAATQKKVERKAPDAGGCLHADPDLG---VLCPTGCQLQEALLQQERPIRNSVDELNN---- 132

  Fly    82 YMGKIAESAATIKDKENEINKLQTKDQTGDELLRKFENLTQVCSAQQSSFTTAIKEKD------E 140
                                                 |:..|.....|||......||      :
Human   133 -------------------------------------NVEAVSQTSSSSFQYMYLLKDLWQKRQK 160

  Fly   141 QIKELEQKVKVYETRLKRKQHVLAELRKLNGSSAL-----LIEHLKGKVVYFERKFREKKDDLLA 200
            |:|:.|..|..|.:.|::.|..:.|....|..:.|     ::|:|:.|:       ::.:.|:.|
Human   161 QVKDNENVVNEYSSELEKHQLYIDETVNSNIPTNLRVLRSILENLRSKI-------QKLESDVSA 218

  Fly   201 DWEAATTSC-----VPF-------------GRSPGIHLIHLPGFL-PFLVPCEGQTAAGPGWTCI 246
            ..|...|.|     :|.             |.:..::||.....: |:.|.|:..|..| |||.|
Human   219 QMEYCRTPCTVSCNIPVVSGKECEEIIRKGGETSEMYLIQPDSSVKPYRVYCDMNTENG-GWTVI 282

  Fly   247 QRRLDGSVNFYRNWDAYSKGFGK------------LNGEFFIGLEKLHRLTSSQPHELYISIRRF 299
            |.|.||||:|.|.||.|.:|||.            |.||:::|.:|:.:||...|.||.|.:..:
Human   283 QNRQDGSVDFGRKWDPYKQGFGNVATNTDGKNYCGLPGEYWLGNDKISQLTRMGPTELLIEMEDW 347

  Fly   300 GGETSYAHYDDFLIGSEEEGYELKLLGHYQGNASDAL-----------RT---HDKMKFSTYDRD 350
            .|:...|||..|.:.:|...|::. :..|:|.|.:||           ||   |:.|.|||||||
Human   348 KGDKVKAHYGGFTVQNEANKYQIS-VNKYRGTAGNALMDGASQLMGENRTMTIHNGMFFSTYDRD 411

  Fly   351 NDAF----THMNCAEHHQGAWWYDFCSRSNLNGRYFKG--------EVDNPQSIYWEPWY-SFRS 402
            ||.:    ....|::...|.|||:.|..:|.||||:.|        :......:.|..|. |:.|
Human   412 NDGWLTSDPRKQCSKEDGGGWWYNRCHAANPNGRYYWGGQYTWDMAKHGTDDGVVWMNWKGSWYS 476

  Fly   403 LKSVQMLIRP 412
            ::.:.|.|||
Human   477 MRKMSMKIRP 486

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8642	NP_610396.2	GluZincin	72..>163	CDD:301352	15/96 (16%)
		FReD	213..413	CDD:238040	82/240 (34%)
FGB	NP_005132.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	44..75		123/465 (26%)
		Beta-chain polymerization, binding distal domain of another fibrin	45..47
		Fib_alpha	92..234	CDD:312286	35/192 (18%)
		FReD	237..486	CDD:294064	80/250 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2579
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X25
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.810