DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8642 and Y43C5A.2

DIOPT Version :9

Sequence 1:	NP_610396.2	Gene:	CG8642 / 35845	FlyBaseID:	FBgn0033312	Length:	429	Species:	Drosophila melanogaster
Sequence 2:	NP_501883.1	Gene:	Y43C5A.2 / 177911	WormBaseID:	WBGene00012782	Length:	452	Species:	Caenorhabditis elegans

Alignment Length:	232	Identity:	61/232 - (26%)
Similarity:	91/232 - (39%)	Gaps:	50/232 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   206 TTSCVPFG----------------------RSPGIHLIHLPGFLPFLVPCEGQTAAGPGWTCIQR 248
            ||:.|||.                      .|.|:..|: |...|..|.|:  |.:...:|.||.
Worm   175 TTTEVPFTGSTLPPTTTPKPPMDCSEISNLTSSGVQTIY-PNGSPVQVYCD--TTSYGTYTVIQS 236

  Fly   249 R--LDGSVNFYRNWDAYSKGFGKLNGE--FFIGLEKLHRLTSSQPHELYISIRRFGGETSYAH-- 307
            |  ...:|||...:|.|:...|....|  |:.||:.::.|:.::|:.|.|.:  ..|....|.
Worm   237 RGATGENVNFNITYDKYTDIIGTPGKETNFWFGLDNMNHLSGAKPYRLQIDL--CCGTLLVAKQI 299

  Fly   308 YDDFLIGSEEEGYELKLLGHYQGNASDALRTHDKM--KFSTYDR--------DNDAFTHMN---C 359
            |..|.:|:.|.||.|.......|.......|:..:  ||||:|.        |.|.|.:.:   .
Worm   300 YHSFKVGTAEYGYNLTATADISGIGLAYSSTYTDLGAKFSTFDNFTGPLGKDDCDEFQYFDDSGV 364

  Fly   360 AEHHQGAWWYDFCSRSNLNGRYF---KGEVDNPQSIY 393
            .....|.|||..|. :||||.::   .|....|..::
Worm   365 QSQPYGGWWYGSCG-NNLNGFWYPKRNGNCTVPDEVF 400

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8642	NP_610396.2	GluZincin	72..>163	CDD:301352
CG8642	NP_610396.2	FReD	213..413	CDD:238040	56/225 (25%)
Y43C5A.2	NP_501883.1	FReD	196..438	CDD:238040	56/211 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2579
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900