DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8642 and Fcnb

DIOPT Version :9

Sequence 1:	NP_610396.2	Gene:	CG8642 / 35845	FlyBaseID:	FBgn0033312	Length:	429	Species:	Drosophila melanogaster
Sequence 2:	XP_006497739.1	Gene:	Fcnb / 14134	MGIID:	1341158	Length:	322	Species:	Mus musculus

Alignment Length:	157	Identity:	56/157 - (35%)
Similarity:	82/157 - (52%)	Gaps:	18/157 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   188 ERKFREKKDDLLADWEAATTSCVPFGRS-----------PGIHLIHLPGFLPFLVPCEGQTAAGP 241
            |:..|.:|.|     ...:.||....|:           .|.:.|:||...|..|.|:..|..|
Mouse    83 EKGIRGEKGD-----SGPSQSCATGPRTCKELLTQGHFLTGWYTIYLPDCRPLTVLCDMDTDGG- 141

  Fly   242 GWTCIQRRLDGSVNFYRNWDAYSKGFGKLNGEFFIGLEKLHRLTSSQPHELYISIRRFGGETSYA 306
            |||..||||||||:|:|:|.:|.:|||...|||::|.:.:|.||:....||.:.:..|.|:..:|
Mouse   142 GWTVFQRRLDGSVDFFRDWTSYKRGFGSQLGEFWLGNDNIHALTTQGTSELRVDLSDFEGKHDFA 206

  Fly   307 HYDDFLIGSEEEGYELKLLGHYQGNAS 333
            .|..|.|..|.|.|:| :||::.|..:
Mouse   207 KYSSFQIQGEAEKYKL-ILGNFLGGGA 232

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8642	NP_610396.2	GluZincin	72..>163	CDD:301352
CG8642	NP_610396.2	FReD	213..413	CDD:238040	50/132 (38%)
Fcnb	XP_006497739.1	Collagen	40..95	CDD:189968	4/16 (25%)
Fcnb	XP_006497739.1	FReD	103..>238	CDD:238040	50/132 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	187	1.000	Domainoid score	I3330
eggNOG	1	0.900	-	-		E1_KOG2579
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000029
OrthoInspector	1	1.000	-	-		otm42379
orthoMCL	1	0.900	-	-		OOG6_100073
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X25
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.710