Protein Alignment CG8642 and Angpt1

DIOPT Version :10

• Sequence 1: NP_610396.2
• Gene: CG8642 / 35845
• FlyBaseID: FBgn0033312
• Length: 429
• Species: Drosophila melanogaster
• Sequence 2: NP_033770.2
• Gene: Angpt1 / 11600
• MGIID: 108448
• Length: 498
• Species: Mus musculus
• Alignment Length: 443
• Identity: 124/443 - (27%)
• Similarity: 189/443 - (42%)
• Gaps: 68/443 - (15%)

  Fly     1 MEYYSIILILIMLPSAWCLQVPSKIKSTTKAPVKEIPPT---NGT----QIGN--VTAVAPVPEK 56
            ||.|          :.|..::.:.|....|:.:.:|...   |.|    :||.  ::..|....|
Mouse    90 MENY----------TQWLQKLENYIVENMKSEMAQIQQNAVQNHTATMLEIGTSLLSQTAEQTRK 144

  Fly    57 LAEVHID-QHKTIRISKGDLDDLLDVYMGKIAESAATIKDKENEINKLQTKD------------- 107
            |.:|... .::|.|:....|::.|..|  |:.:.   :..:.|||.|:..|:
Mouse   145 LTDVETQVLNQTSRLEIQLLENSLSTY--KLEKQ---LLQQTNEILKIHEKNSLLEHKILEMEGK 204

  Fly   108 --QTGDELLRKFENLTQVCSAQQSSFTTAIKEKDEQIKELEQKVKVYETRLKRKQHVLAELRKLN 170
              :..|.|..:.|||..:.|.|    |..|:|.::|:........:.:.:.......:..|..|.
Mouse   205 HKEELDTLKEEKENLQGLVSRQ----TFIIQELEKQLSRATNNNSILQKQQLELMDTVHNLISLC 265

  Fly   171 GSSALLIEHLKGKVVYFERKFREKKDDLLADWEAATTSCVPFGRSPGIHLIHLPGFLPFLVPCEG 235
            ....:|   |||.....|:.||:..|...|.:..:....:.|...|.          |..|.| .
Mouse   266 TKEGVL---LKGGKREEEKPFRDCADVYQAGFNKSGIYTIYFNNMPE----------PKKVFC-N 316

  Fly   236 QTAAGPGWTCIQRRLDGSVNFYRNWDAYSKGFGKLNGEFFIGLEKLHRLTSSQPHELYISIRRFG 300
            ....|.|||.||.|.|||::|.|.|..|..|||..:||:::|.|.:..:||.:.:.|.|.:..:.
Mouse   317 MDVNGGGWTVIQHREDGSLDFQRGWKEYKMGFGNPSGEYWLGNEFIFAITSQRQYMLRIELMDWE 381

  Fly   301 GETSYAHYDDFLIGSEEEGYELKLLGHYQGNA--SDALRTHDKMKFSTYDRDNDAFTHMNCAEHH 363
            |..:|:.||.|.||:|::.|.|.|.|| .|.|  ..:|..|. ..|||.|.|||. ....||...
Mouse   382 GNRAYSQYDRFHIGNEKQNYRLYLKGH-TGTAGKQSSLILHG-ADFSTKDADNDN-CMCKCALML 443

  Fly   364 QGAWWYDFCSRSNLNGRYFKGEVDNPQSIYWEPWYSFR----SLKSVQMLIRP 412
            .|.||:|.|..|||||.::... .|...:....|:.|:    ||:|..|:|||
Mouse   444 TGGWWFDACGPSNLNGMFYTAG-QNHGKLNGIKWHYFKGPSYSLRSTTMMIRP 495

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8642	NP_610396.2	MAD	71..>198	CDD:461677	30/141 (21%)
		FReD	213..413	CDD:238040	75/206 (36%)
Angpt1	NP_033770.2	Mplasa_alph_rch	<105..>258	CDD:275316	32/161 (20%)
		FReD	281..496	CDD:238040	80/230 (35%)