DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8642 and Fcnb

DIOPT Version :9

Sequence 1:	NP_610396.2	Gene:	CG8642 / 35845	FlyBaseID:	FBgn0033312	Length:	429	Species:	Drosophila melanogaster
Sequence 2:	NP_446086.1	Gene:	Fcnb / 114091	RGDID:	621222	Length:	319	Species:	Rattus norvegicus

Alignment Length:	238	Identity:	87/238 - (36%)
Similarity:	126/238 - (52%)	Gaps:	22/238 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   188 ERKFREKKDDLLADWEAATTSCVPFGRS-----------PGIHLIHLPGFLPFLVPCEGQTAAGP 241
            |:..|.:|.|     ...:.||....|:           .|.:.|:||...|..|.|:..|..|
  Rat    88 EKGVRGEKGD-----TGPSQSCATGPRTCKELLTRGYFLTGWYTIYLPDCRPLTVLCDMDTDGG- 146

  Fly   242 GWTCIQRRLDGSVNFYRNWDAYSKGFGKLNGEFFIGLEKLHRLTSSQPHELYISIRRFGGETSYA 306
            |||..|||:||:|:|:|:|.:|.:|||...|||::|.:.:|.||:...:||.:.:..|.|...:|
  Rat   147 GWTVFQRRIDGTVDFFRDWTSYKQGFGSQLGEFWLGNDNIHALTTQGTNELRVDLADFDGNHDFA 211

  Fly   307 HYDDFLIGSEEEGYELKLLGHY-QGNASDALRTHDKMKFSTYDRDNDAFTHMNCAEHHQGAWWYD 370
            .|..|.|..|.|.|:| :||:: .|.|.|:|.:.:.|.|||.|:|||..: .|||..:.|||||.
  Rat   212 KYSSFQIQGEAEKYKL-ILGNFLGGGAGDSLTSQNNMLFSTKDQDNDQGS-SNCAVRYHGAWWYS 274

  Fly   371 FCSRSNLNGRYFKG-EVDNPQSIYWEPWYSFR-SLKSVQMLIR 411
            .|..|||||.|.:| .......:.|:.|..:. |.|..:|.:|
  Rat   275 DCHTSNLNGLYLRGLHKSYANGVNWKSWKGYNYSYKVSEMKVR 317

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8642	NP_610396.2	GluZincin	72..>163	CDD:301352
CG8642	NP_610396.2	FReD	213..413	CDD:238040	81/213 (38%)
Fcnb	NP_446086.1	Collagen	45..100	CDD:189968	4/16 (25%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	53..106		6/22 (27%)
		FReD	108..317	CDD:238040	80/211 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2579
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000029
OrthoInspector	1	1.000	-	-		mtm12326
orthoMCL	1	0.900	-	-		OOG6_100073
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X25
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.710