DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8642 and LOC108179162

DIOPT Version :9

Sequence 1:	NP_610396.2	Gene:	CG8642 / 35845	FlyBaseID:	FBgn0033312	Length:	429	Species:	Drosophila melanogaster
Sequence 2:	XP_017211437.2	Gene:	LOC108179162 / 108179162	-ID:	-	Length:	243	Species:	Danio rerio

Alignment Length:	235	Identity:	91/235 - (38%)
Similarity:	131/235 - (55%)	Gaps:	19/235 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   198 LLADWEAATTS------CVPFGRS----PGIHLIHLPGFLPFLVPC----EGQTAAGPGWTCIQR 248
            ||:.:.|:..|      |....||    .||:.|:..|.:|..|.|    :|:.....|||..||
Zfish    10 LLSVFTASVVSGFKPFDCSEIYRSGQTVSGIYSIYPAGDIPVWVYCQMISDGKDEENGGWTVFQR 74

  Fly   249 RLDGSVNFYRNWDAYSKGFGKLNGEFFIGLEKLHRLTSSQPHELYISIRRFGGETSYAHYDDFLI 313
            |:||.:|||:.|:.|.:|||...||:::|||.|::||..:...|.:.:..|.|...:|.|..|.:
Zfish    75 RMDGRINFYQPWEEYKRGFGTTEGEYWLGLENLYQLTRHKKFMLRVDLEDFEGRRGFAQYSSFSV 139

  Fly   314 GSEEEGYELKLLGHYQGNASDALRTHDKMKFSTYDRDNDAFTHMNCAEHHQGAWWYDFCSRSNLN 378
            |||.|||.|::.|...|.|.|:|..|:..||||:|:|.||:.. |||:...||:|:.:|..:|.|
Zfish   140 GSEAEGYRLQVSGFTDGGAGDSLTDHNDQKFSTFDKDQDAYGD-NCAQEFLGAFWFKYCHNTNPN 203

  Fly   379 GRYFKGEVDNPQSI--YWEPWY-SFR-SLKSVQMLIRPKS 414
            |.|..||.|....|  .|..|. ||. |:||:.::|:.||
Zfish   204 GVYLWGEDDTHFGIGVVWSTWKDSFTVSMKSLSLMIKSKS 243

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8642	NP_610396.2	GluZincin	72..>163	CDD:301352
CG8642	NP_610396.2	FReD	213..413	CDD:238040	84/211 (40%)
LOC108179162	XP_017211437.2	FReD	24..242	CDD:238040	85/218 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2579
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900