DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8642 and fcn2l

DIOPT Version :9

Sequence 1:	NP_610396.2	Gene:	CG8642 / 35845	FlyBaseID:	FBgn0033312	Length:	429	Species:	Drosophila melanogaster
Sequence 2:	XP_004917606.2	Gene:	fcn2l / 101735093	XenbaseID:	XB-GENE-22167163	Length:	301	Species:	Xenopus tropicalis

Alignment Length:	234	Identity:	87/234 - (37%)
Similarity:	122/234 - (52%)	Gaps:	28/234 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   186 YFERKFREKKD--DLLADWEAATTSCVPFGRSPGIHLIHLPGFLPFLVPCEGQTAAGPGWTCIQR 248
            |..|..:|..|  ::|:||                ::|:..|..|..|.|:..|..| ||...||
Frog    88 YAARNCKELLDQGEVLSDW----------------YIIYPDGVQPMKVLCDMHTDGG-GWIVFQR 135

  Fly   249 RLDGSVNFYRNWDAYSKGFGKLNGEFFIGLEKLHRLTSSQPHELYISIRRFGGETSYAHYDDFLI 313
            |.||||:|:|:|.:|..|||....||::|.:.||:||||...||.:.::.|.....:|.|:.|.|
Frog   136 RWDGSVDFFRDWKSYKSGFGSRLNEFWLGNDNLHKLTSSGTWELRVDLQDFENAKHFAKYESFRI 200

  Fly   314 GSEEEGYELKLLGHYQGNASDALRTHDKMKFSTYDRDNDAFTHMNCAEHHQGAWWYDFCSRSNLN 378
            ..|.|.::|.:.....||..||::.|:.|.|||.|:|||.... :||:.::|.|||:.|..||||
Frog   201 LGESEKFKLLIGAMKGGNIEDAMKVHNTMPFSTKDQDNDILPE-HCADRYKGGWWYNGCHHSNLN 264

  Fly   379 GRYFKGEVDN-PQSIYWEPWYSFR----SLKSVQMLIRP 412
            |.|..|...| .:.|   .||..|    |.|..:|.|||
Frog   265 GLYLLGSHSNTAEGI---NWYGGRGHNYSYKRSEMKIRP 300

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8642	NP_610396.2	GluZincin	72..>163	CDD:301352
CG8642	NP_610396.2	FReD	213..413	CDD:238040	80/205 (39%)
fcn2l	XP_004917606.2	Collagen	38..>79	CDD:396114
fcn2l	XP_004917606.2	FReD	91..300	CDD:238040	84/229 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000029
OrthoInspector	1	1.000	-	-		mtm14088
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X25
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.000