DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8642 and mfap4.2

DIOPT Version :9

Sequence 1:	NP_610396.2	Gene:	CG8642 / 35845	FlyBaseID:	FBgn0033312	Length:	429	Species:	Drosophila melanogaster
Sequence 2:	XP_012826893.1	Gene:	mfap4.2 / 100488329	XenbaseID:	XB-GENE-22167947	Length:	261	Species:	Xenopus tropicalis

Alignment Length:	209	Identity:	73/209 - (34%)
Similarity:	112/209 - (53%)	Gaps:	15/209 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   214 RSPGIHLIHLPG---FLPFLVPCEGQTAAGPGWTCIQRRLDGSVNFYRNWDAYSKGFGKLNGEFF 275
            :..|:::|:..|   .||  |.|: .|.....||.||:|.|||::|.|.|..|..|||:.:.|::
Frog    46 KEDGVYIIYPAGSSSALP--VYCD-MTTDEAKWTVIQKRFDGSLSFSRGWTDYKLGFGRADEEYW 107

  Fly   276 IGLEKLHRLTSSQPHELYISIRRFGGETSYAHYDDF-----LIGSEEEGYELKLLGHYQGNASDA 335
            :||..:::||..:.:.|.|.:..|...|::|.|.||     .|..|::||.|.:.|...|.|.|:
Frog   108 LGLHNIYQLTLQKKYMLRIELGDFENNTAHAEYTDFSLSPNAINPEDDGYTLFVDGFIDGGAGDS 172

  Fly   336 LRTHDKMKFSTYDRDNDAFTHMNCAEHHQGAWWYDFCSRSNLNGRYFKGE--VDNPQSIYWEPWY 398
            |..|:.|||||:|.|.|.: ..|||..:...:|:..|..:|:||.|.:..  ..:...|.|..|.
Frog   173 LTFHNGMKFSTFDHDQDTY-QQNCAFLYSSGFWFKGCHLANINGPYLQDATYTSSGNGITWTRWK 236

  Fly   399 SFR-SLKSVQMLIR 411
            .|. |||:.::.||
Frog   237 GFNYSLKTTEIKIR 250

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8642	NP_610396.2	GluZincin	72..>163	CDD:301352
CG8642	NP_610396.2	FReD	213..413	CDD:238040	73/209 (35%)
mfap4.2	XP_012826893.1	FReD	32..252	CDD:238040	73/209 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000029
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X25
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.000