DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8642 and fga

DIOPT Version :9

Sequence 1:	NP_610396.2	Gene:	CG8642 / 35845	FlyBaseID:	FBgn0033312	Length:	429	Species:	Drosophila melanogaster
Sequence 2:	XP_002933535.3	Gene:	fga / 100038060	XenbaseID:	XB-GENE-478771	Length:	761	Species:	Xenopus tropicalis

Alignment Length:	462	Identity:	136/462 - (29%)
Similarity:	196/462 - (42%)	Gaps:	105/462 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 VPSKIKSTTKAPVKEIPPT-NGTQIGNVTAVAPVPEKLAEVHIDQ--------HKTIRISKG-DL 75
            |..::.||.:.|.:||..| :|         .|..|||.::..|.        .:.|.||.| .|
Frog   330 VKRRVVSTPEGPKEEITETYSG---------GPECEKLGKLSTDDTFQGGSDGTRVIHISGGSSL 385

  Fly    76 DDLLDV--------YMGKIAESAATIKDKENEINKLQTKDQTGDELLRKFENLTQVCSAQQSSFT 132
            .|:..:        ..||..:::.| ....:..:|: |.|...|....:|::.:.. .....|||
Frog   386 GDISKIPSFEEFLSSSGKKTQTSQT-SSSSSSSSKV-THDVFTDLGEDEFDDFSHT-GLDSPSFT 447

  Fly   133 TAIKEKDEQIKELEQKVKVYETRLKRKQHVLAELRKLNGSS----ALLIEHLKGKVVY------- 186
            ...||....|.:.                |::......|||    ...|:.:|...|:
Frog   448 PLQKEGSSTITKT----------------VVSSSSSSRGSSKDGTQFDIKSMKSGPVFTDFGPIQ 496

  Fly   187 ----------FERKFREKKDDLLADWEAATTSCV----PFGRSPGIHLIHLPGFLPFL-VPCEGQ 236
                      |:.:...|:..|:.|:.......:    ..|...||..|...|....| |.|:..
Frog   497 HDNSEEDRPDFQARTVRKEMKLVGDYTGKDCDDIRQKHSSGAKSGIFKIRPEGSTKVLSVYCDQD 561

  Fly   237 TAAGPGWTCIQRRLDGSVNFYRNWDAYSKGFGKLN----GEFFIGLEKLHRLTSSQPHELYISIR 297
            |..| ||..||:|.||||||.|.|..|..|||.::    ||.::|.|.:|.||.... .|.|.:.
Frog   562 TQLG-GWILIQQRQDGSVNFNRTWQDYKNGFGSVDAGGKGEVWLGNENIHLLTQKDT-ILRIELE 624

  Fly   298 RFGGETSYAHYDDFLIGSEEEGYELKLLGHYQGNASDAL----------RTHDKMKFSTYDRDND 352
            .:.||..||.| :..:|||.||:.|| :..|:|.|.|||          .:|..|||||||||:|
Frog   625 DWSGEKVYAEY-NIQLGSEAEGFTLK-VSQYEGTAGDALIEGSKEDGEYTSHINMKFSTYDRDSD 687

  Fly   353 AFTHMNCAEHHQGAWWYDFCSRSNLNGRYFKG-----------EVDNPQSIYWEPWYSF-RSLKS 405
            .:.. ||||.:.|.|||:.|..|||||.|:.|           |::|  .:.|.|:.:. .|||:
Frog   688 KWEE-NCAEMYGGGWWYNNCQASNLNGIYYIGGQYDPRNNFPYEIEN--GVVWVPFKAADYSLKT 749

  Fly   406 VQMLIRP 412
            |:|.:||
Frog   750 VRMKMRP 756

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8642	NP_610396.2	GluZincin	72..>163	CDD:301352	17/99 (17%)
CG8642	NP_610396.2	FReD	213..413	CDD:238040	92/227 (41%)
fga	XP_002933535.3	Fib_alpha	51..191	CDD:400857
		Fibrinogen_aC	299..372	CDD:403400	13/50 (26%)
		FReD	523..757	CDD:238040	92/241 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910