DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rgr and Zscan25

DIOPT Version :9

Sequence 1:	NP_001163089.2	Gene:	rgr / 35843	FlyBaseID:	FBgn0267792	Length:	889	Species:	Drosophila melanogaster
Sequence 2:	XP_038945553.1	Gene:	Zscan25 / 363872	RGDID:	1308619	Length:	554	Species:	Rattus norvegicus

Alignment Length:	227	Identity:	76/227 - (33%)
Similarity:	105/227 - (46%)	Gaps:	23/227 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   669 SSIPLLHA-----KLAEFLDQNLG---PFRCDIC-------SDLVKTCDQYKVHRSAHDGTQPFI 718
            :|:|.|.|     .|.|.|..:..   ||:|..|       |:||:       |:..|:..:.|.
  Rat   329 TSVPGLPAPQPGVPLPEALSAHSSFWKPFQCPECGKGFSRSSNLVR-------HQRTHEEEKAFG 386

  Fly   719 CTLCGKGFQMPCNLTVHIRRHRRDFPYSCEQCDKRFATSTEVAIHLRTHTGERPYICDLCGKSFK 783
            |..|||||.:...||.|.|.|....||.|.:|.|.|:....:.:|.|:||||:||.|..|.|.|.
  Rat   387 CVECGKGFTLREYLTKHQRTHLGKRPYVCGECWKTFSQRHHLEVHQRSHTGEKPYKCADCWKGFS 451

  Fly   784 TWSFFDIHRRRHLNQSTFHCPICAKGFYEKNRFTDHMNSHWAIRKHLCTVCGKTFTTYGNLKKHT 848
            ......:|||.|..:..:.|. |.|.|........|..:|...:.:.|.||||.|:....|.:|.
  Rat   452 RRQHLLVHRRTHTGEKPYTCE-CGKSFSRNANLAVHRRAHTGEKPYGCQVCGKRFSKGERLVRHQ 515

  Fly   849 ELHLAVKKYKCGTCGKRFAQFASLRWHKKREH 880
            .:|...|.|.|..||:.|.|.:.|..|:|.:|
  Rat   516 RIHTGEKPYHCPACGRSFNQRSILNRHQKTQH 547

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rgr	NP_001163089.2	MADF_DNA_bdg	335..420	CDD:287510
		MADF_DNA_bdg	465..551	CDD:287510
		MADF_DNA_bdg	595..682	CDD:287510	6/17 (35%)
		C2H2 Zn finger	691..711	CDD:275368	6/26 (23%)
		C2H2 Zn finger	719..739	CDD:275368	10/19 (53%)
		zf-H2C2_2	731..756	CDD:290200	11/24 (46%)
		COG5048	742..>824	CDD:227381	27/81 (33%)
		C2H2 Zn finger	747..767	CDD:275368	6/19 (32%)
		zf-H2C2_2	763..784	CDD:290200	12/20 (60%)
		C2H2 Zn finger	775..795	CDD:275368	7/19 (37%)
		C2H2 Zn finger	803..818	CDD:275368	4/14 (29%)
		C2H2 Zn finger	831..851	CDD:275368	8/19 (42%)
		C2H2 Zn finger	859..877	CDD:275368	7/17 (41%)
Zscan25	XP_038945553.1	SCAN	38..120	CDD:396558
		KRAB_A-box	241..>269	CDD:413388
		COG5048	<348..542	CDD:227381	66/201 (33%)
		C2H2 Zn finger	359..379	CDD:275368	6/26 (23%)
		C2H2 Zn finger	387..407	CDD:275368	10/19 (53%)
		C2H2 Zn finger	415..435	CDD:275368	6/19 (32%)
		C2H2 Zn finger	443..463	CDD:275368	7/19 (37%)
		C2H2 Zn finger	471..490	CDD:275368	5/19 (26%)
		C2H2 Zn finger	498..518	CDD:275368	8/19 (42%)
		C2H2 Zn finger	526..545	CDD:275368	7/18 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910