DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rgr and sna

DIOPT Version :9

Sequence 1:	NP_001163089.2	Gene:	rgr / 35843	FlyBaseID:	FBgn0267792	Length:	889	Species:	Drosophila melanogaster
Sequence 2:	NP_476732.1	Gene:	sna / 34908	FlyBaseID:	FBgn0003448	Length:	390	Species:	Drosophila melanogaster

Alignment Length:	190	Identity:	53/190 - (27%)
Similarity:	80/190 - (42%)	Gaps:	31/190 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   665 SEDSSSIPLLHAKLAEFLDQNLGPFRCDICSDLVKTCDQYKVHRSAHDGTQPFICTLCGKGFQMP 729
            |..|:|:...|||...        |:||.|..:..|......||..|       |...      .
  Fly   229 SASSASVAANHAKNYR--------FKCDECQKMYSTSMGLSKHRQFH-------CPAA------E 272

  Fly   730 CNLTVHIRRHRRDFPYSCEQCDKRFATSTEVAIHLRTHTGERPYICDLCGKSFKTWSFFDIHRRR 794
            ||        :....:|||:|.|.:.|...:.:|:||||  .|..|.:|||:|........|.|.
  Fly   273 CN--------QEKKTHSCEECGKLYTTIGALKMHIRTHT--LPCKCPICGKAFSRPWLLQGHIRT 327

  Fly   795 HLNQSTFHCPICAKGFYEKNRFTDHMNSHWAIRKHLCTVCGKTFTTYGNLKKHTELHLAV 854
            |..:..|.||.|.:.|.:::....|..:|..::|:.|.||.|:|:....|.||:..:..:
  Fly   328 HTGEKPFQCPDCPRSFADRSNLRAHQQTHVDVKKYACQVCHKSFSRMSLLNKHSSSNCTI 387

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rgr	NP_001163089.2	MADF_DNA_bdg	335..420	CDD:287510
		MADF_DNA_bdg	465..551	CDD:287510
		MADF_DNA_bdg	595..682	CDD:287510	6/16 (38%)
		C2H2 Zn finger	691..711	CDD:275368	6/19 (32%)
		C2H2 Zn finger	719..739	CDD:275368	3/19 (16%)
		zf-H2C2_2	731..756	CDD:290200	6/24 (25%)
		COG5048	742..>824	CDD:227381	26/81 (32%)
		C2H2 Zn finger	747..767	CDD:275368	7/19 (37%)
		zf-H2C2_2	763..784	CDD:290200	11/20 (55%)
		C2H2 Zn finger	775..795	CDD:275368	7/19 (37%)
		C2H2 Zn finger	803..818	CDD:275368	4/14 (29%)
		C2H2 Zn finger	831..851	CDD:275368	8/19 (42%)
		C2H2 Zn finger	859..877	CDD:275368
sna	NP_476732.1	C2H2 Zn finger	308..328	CDD:275368	7/19 (37%)
		zf-H2C2_2	321..344	CDD:290200	7/22 (32%)
		zf-C2H2	334..356	CDD:278523	6/21 (29%)
		C2H2 Zn finger	336..356	CDD:275368	5/19 (26%)
		zf-H2C2_2	348..373	CDD:290200	8/24 (33%)
		C2H2 Zn finger	364..380	CDD:275368	6/15 (40%)
		C2H2 Zn finger	247..267	CDD:275368	6/19 (32%)
		C2H2 Zn finger	282..302	CDD:275368	7/19 (37%)
		zf-C2H2	306..328	CDD:278523	7/21 (33%)
		COG5048	307..>356	CDD:227381	14/48 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45468408
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930