DRSC/TRiP Functional Genomics Resources

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Protein Alignment rgr and ZSCAN1

DIOPT Version :10

Sequence 1:NP_001163089.2 Gene:rgr / 35843 FlyBaseID:FBgn0267792 Length:889 Species:Drosophila melanogaster
Sequence 2:XP_006723212.1 Gene:ZSCAN1 / 284312 HGNCID:23712 Length:448 Species:Homo sapiens


Alignment Length:395 Identity:95/395 - (24%)
Similarity:136/395 - (34%) Gaps:82/395 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly   516 EIQKLRTRYRKELRMVIKHKGLYLPKLW----------CYDEMEFLQPILQEQIFNKISKKIGV- 569
            |.|:|  |:|:....|.....|.|.:||          ...:.:.|:.::.||....:..|:.. 
Human    75 EAQRL--RFRQFQYHVASGPHLALGQLWTLCRQWLRPEARSKEQMLELLVLEQFLGALPSKMRTW 137

  Fly   570 VGSNQKTKFIDASSIRFDNTEKQLQFVEIYHNYSALWDVDHPDF-----------RSNTYRSQAL 623
            |.|.......:|:|:..|.|:...|.|.:     :|..|:..|:           ||....|||.
Human   138 VQSQGPRSCREAASLVEDLTQMCQQEVLV-----SLDSVEPQDWSFGEEEDGKSPRSQKEPSQAS 197

  Fly   624 GQMLDEINTTFHTSYTAEQLEKT----LFNLRKEFSAQKRKILTESEDSSSIPLLHAKLAEFLDQ 684
            ..:||.:.........:|.||.|    ..:.|.|..|.:...|..|.  :.:||..:...|..|.
Human   198 ELILDAVAAAPALPEESEWLETTQLQQSLHTRAEAEAPRAPGLLGSR--ARLPLKPSIWDEPEDL 260

  Fly   685 NLGPFRCDICSDL-----------------------VKTCDQYKVH----RSAHDGTQPFICTLC 722
            ..||     .|||                       .:..||...|    :....|||..:    
Human   261 LAGP-----SSDLRAEGTVISSPKGPSAQRISPRRRNRNTDQSGRHQPSLKHTKGGTQEAV---- 316

  Fly   723 GKGFQMPCNLTVHIRRHRRDFPYSCEQCDKRFATSTEVAIHLRTHTGERPYICDLCGKSFKTWSF 787
                   ..::|..|..|...|:.|..|...|...|....|.:||..|.|:.|..|||.|...|.
Human   317 -------AGISVVPRGPRGGRPFQCADCGMVFTWVTHFIEHQKTHREEGPFPCPECGKVFLHNSV 374

  Fly   788 FDIHRRRHLNQSTFHCPICAKGFYEKNRFTDHMNSHWAIRK----HLCTVCGKTFTTYGNLKKHT 848
            ...|.:.||.:........:||..|.....|......|.|.    ..|:||||.|....:|..|.
Human   375 LTEHGKIHLLEPPRKKAPRSKGPRESVPPRDGAQGPVAPRSPKRPFQCSVCGKAFPWMVHLIDHQ 439

  Fly   849 ELHLA 853
            :||.|
Human   440 KLHTA 444

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
rgrNP_001163089.2 MADF 334..425 CDD:214738
MADF 466..556 CDD:214738 11/49 (22%)
MADF_DNA_bdg 595..682 CDD:463144 23/101 (23%)
C2H2 Zn finger 691..711 CDD:275368 6/46 (13%)
C2H2 Zn finger 719..739 CDD:275368 2/19 (11%)
COG5048 742..>824 CDD:227381 23/81 (28%)
C2H2 Zn finger 747..767 CDD:275368 5/19 (26%)
C2H2 Zn finger 775..795 CDD:275368 7/19 (37%)
C2H2 Zn finger 803..818 CDD:275368 3/14 (21%)
C2H2 Zn finger 831..851 CDD:275368 8/19 (42%)
C2H2 Zn finger 859..877 CDD:275368
ZSCAN1XP_006723212.1 SCAN 75..162 CDD:460417 20/88 (23%)
C2H2 Zn finger 334..354 CDD:275368 5/19 (26%)
zf-H2C2_2 346..371 CDD:463886 10/24 (42%)
C2H2 Zn finger 362..382 CDD:275368 7/19 (37%)
ZnF_C2H2 420..442 CDD:197676 8/21 (38%)
C2H2 Zn finger 422..442 CDD:275368 8/19 (42%)
Blue background indicates that the domain is not in the aligned region.

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