DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment rgr and Zfp760

DIOPT Version :10

Sequence 1:NP_001163089.2 Gene:rgr / 35843 FlyBaseID:FBgn0267792 Length:889 Species:Drosophila melanogaster
Sequence 2:NP_001397492.1 Gene:Zfp760 / 240034 MGIID:2679257 Length:671 Species:Mus musculus


Alignment Length:644 Identity:147/644 - (22%)
Similarity:242/644 - (37%) Gaps:156/644 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly   314 CADFQSKSRRELERNHEFVGCLLREYERTEKLWNPRHPDYKYNAKRSA-------YGDLAGPLES 371
            |..::....:..|..|..:.....:|:...|:.:...|...||...:|       |.|.:.....
Mouse    58 CGKYEKVLDQHSEHQHVNIQEKSYKYKELGKMVHESSPCTPYNTSSTAENCNKYSYQDASIESSL 122

  Fly   372 ICHRQL-SGAEIFAVLKELRCRYRRELKKVNALGGKYKSRLWYFERMDFLRCVIEN---RRAERE 432
            |.|..: :|.|:|                      |||         :..:|:..|   .::..:
Mouse   123 IRHNSVHTGEELF----------------------KYK---------ECGKCLCSNICPNQSIHD 156

  Fly   433 AKISNESTESEKSCET-------------DADSCGK-----SSL-YHEVLSFILDAFKRQECLWN 478
            .|:.::.|||:|.|.:             .|.:|||     ||| .|:.|......:|.:||   
Mouse   157 IKMEHKYTESDKLCGSTHRLVQQRTHSGEKAHNCGKCFRSCSSLSTHQRLHTGEKPWKCKEC--- 218

  Fly   479 PQHYDYTTCCKTELFRDISVQLQEELNYELSGEE--CCNE-------IQKLRTRYRKELRMVIKH 534
                       .:.|:.:| .|:...... :||:  .|||       :.:|::.||       .|
Mouse   219 -----------GKSFKWLS-HLKAHCRIH-TGEKPFKCNECDKGFSRLSRLKSHYR-------TH 263

  Fly   535 KGLYLPKLWCYDEMEFLQPILQEQIFNKISK-----KIGVVGSNQKTK-----FIDASSIRFDNT 589
            .|   .|.:..:|.        .:.|:::|:     :|.......|.|     |...:.:   :|
Mouse   264 TG---EKPYKCEEC--------GKCFSRLSRLKNHYRIHTGEKPYKCKECGKSFTHCTGL---ST 314

  Fly   590 EKQLQFVE----------IYHNYSALWDVDHPDFRSNTYRSQALGQMLDEIN--------TTFHT 636
            .:::...|          .:|..|.|.:......|...|:.:..|:....::        .|..|
Mouse   315 HQKIHTGEKPHKCKNCGKSFHLLSTLKEHFRVHTREKPYKCKECGKFFHWLSGLKSHYRIHTGET 379

  Fly   637 SYTAEQLEKTLFNLRKEFSAQKRKILTESEDSSSIPL-------------LHAKLAEFLDQNLGP 688
            .|..::.:|:.    .:.|..|....|.:.:.|...|             .|.|:  ..|:.  |
Mouse   380 PYKCKECDKSF----SQLSRLKSHYRTHTGEKSCKCLECDKYFTQCTALKRHQKI--HTDEK--P 436

  Fly   689 FRCDICSDLVKTCDQYKVHRSAHDGTQPFICTLCGKGFQMPCNLTVHIRRHRRDFPYSCEQCDKR 753
            ::|:.||.........|.|...|.|.:|:.|..|||.......|..|.|.|..:.||.|::|||.
Mouse   437 YKCEECSKCFYVLSHLKSHCRTHTGEKPYKCEECGKCLSQLSKLKSHYRIHTGEKPYKCKECDKS 501

  Fly   754 FATSTEVAIHLRTHTGERPYICDLCGKSFKTWSFFDIHRRRHLNQSTFHCPICAKGFYEKNRFTD 818
            |...|.::.|.:.||||:||.|..|||||...|....|.|.|..:..::|..|.|.|:..:....
Mouse   502 FTHCTALSTHQKIHTGEKPYSCKDCGKSFYLLSRLKEHYRVHTGEKPYNCKECGKFFHWLSNLKR 566

  Fly   819 HMNSHWAIRKHLCTVCGKTFTTYGNLKKHTELHLAVKKYKCGTCGKRFAQFASLRWHKK 877
            |...|...:.:.|..|.|:||...:||.|.::|..||.|||..|.|.|...::|:.|.:
Mouse   567 HSRIHTGEKPYKCEECDKSFTHCSSLKAHQKIHAGVKPYKCEECSKSFYWLSNLKTHSR 625

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
rgrNP_001163089.2 MADF 334..425 CDD:214738 17/98 (17%)
MADF 466..556 CDD:214738 18/98 (18%)
MADF_DNA_bdg 595..682 CDD:463144 18/117 (15%)
C2H2 Zn finger 691..711 CDD:275368 5/19 (26%)
C2H2 Zn finger 719..739 CDD:275368 7/19 (37%)
COG5048 742..>824 CDD:227381 30/81 (37%)
C2H2 Zn finger 747..767 CDD:275368 7/19 (37%)
C2H2 Zn finger 775..795 CDD:275368 9/19 (47%)
C2H2 Zn finger 803..818 CDD:275368 4/14 (29%)
C2H2 Zn finger 831..851 CDD:275368 8/19 (42%)
C2H2 Zn finger 859..877 CDD:275368 6/17 (35%)
Zfp760NP_001397492.1 KRAB 13..>55 CDD:214630
C2H2 Zn finger 137..182 CDD:275368 10/53 (19%)
C2H2 Zn finger 188..207 CDD:275368 7/18 (39%)
COG5048 211..586 CDD:227381 95/419 (23%)
C2H2 Zn finger 215..235 CDD:275368 5/34 (15%)
C2H2 Zn finger 243..263 CDD:275368 6/26 (23%)
C2H2 Zn finger 271..291 CDD:275368 3/27 (11%)
C2H2 Zn finger 299..319 CDD:275368 3/22 (14%)
C2H2 Zn finger 327..347 CDD:275368 3/19 (16%)
C2H2 Zn finger 355..375 CDD:275368 1/19 (5%)
C2H2 Zn finger 383..403 CDD:275368 3/23 (13%)
C2H2 Zn finger 411..431 CDD:275368 3/21 (14%)
C2H2 Zn finger 439..459 CDD:275368 5/19 (26%)
C2H2 Zn finger 467..487 CDD:275368 7/19 (37%)
C2H2 Zn finger 495..515 CDD:275368 7/19 (37%)
C2H2 Zn finger 523..543 CDD:275368 9/19 (47%)
C2H2 Zn finger 551..571 CDD:275368 5/19 (26%)
SFP1 <573..623 CDD:227516 18/49 (37%)
C2H2 Zn finger 579..599 CDD:275368 8/19 (42%)
C2H2 Zn finger 607..627 CDD:275368 6/19 (32%)
zf-H2C2_2 619..644 CDD:463886 2/7 (29%)
C2H2 Zn finger 635..655 CDD:275368
Blue background indicates that the domain is not in the aligned region.

Return to query results.
Submit another query.