DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rgr and che-1

DIOPT Version :9

Sequence 1:	NP_001163089.2	Gene:	rgr / 35843	FlyBaseID:	FBgn0267792	Length:	889	Species:	Drosophila melanogaster
Sequence 2:	NP_001076598.1	Gene:	che-1 / 183847	WormBaseID:	WBGene00000483	Length:	273	Species:	Caenorhabditis elegans

Alignment Length:	326	Identity:	77/326 - (23%)
Similarity:	118/326 - (36%)	Gaps:	107/326 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   572 SNQKTKFIDASSIRFDNTEKQLQFVEIYHNYSALWDVDH-PDFRSNTYRSQALGQMLDEI----N 631
            :|..|.|.|::     |...|:|   ::|.|...:..|. ....|:....|||.|..:.|    |
Worm     8 NNNNTDFFDSA-----NYIPQMQ---MHHGYQDFYASDSTSSMPSSGTTQQALQQTENGIIQGQN 64

  Fly   632 TTFHTSY---------------TAEQLEKTLFNLRKEFSAQKRKILTESEDSSSIPLLHAKLAEF 681
            .:.|.:|               ...|||            .:...||.|..:::
Worm    65 GSDHGAYGGWRQHDWNSTSSWSIGNQLE------------MENGTLTMSHGATN----------- 106

  Fly   682 LDQNLGPFRCDICSDLVKTCDQYK-------------------------VHR-SAHDGTQPFICT 720
             |.|:...:..:.|:.: |.|.::                         |.| .|....:||.|.
Worm   107 -DGNIRNNQQMMTSNHI-TTDSFRQIPPSGLCYMDPTPSLRLPKKEPLPVQRPMARSTPKPFRCQ 169

  Fly   721 LCGKGFQMPCNLTVHIRRHRRDFPYSCEQCDKRFATSTEVAIHLRTHTGERPYICDLCGKSFKTW 785
            .|||.|....|||.|.|.|..:.|:.|..|::.|:.|:.:..|.|||||||||
Worm   170 TCGKAFSQAANLTAHKRIHTGEKPFMCPVCNRPFSQSSSLVTHRRTHTGERPY------------ 222

  Fly   786 SFFDIHRRRHLNQSTFHCPICAKGFYEKNRFTDHMNSHWAIRKHLCTVCGKTFTTYGNLKKHTEL 850
                            .|..|.|.|.:.:..|.|:.:|...:.::|::|...||..|||.:|.:.
Worm   223 ----------------PCAQCEKAFTDSSTLTKHLRTHTGHKPYVCSICMMKFTQSGNLHRHMKT 271

  Fly   851 H 851
            |
Worm   272 H 272

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rgr	NP_001163089.2	MADF_DNA_bdg	335..420	CDD:287510
		MADF_DNA_bdg	465..551	CDD:287510
		MADF_DNA_bdg	595..682	CDD:287510	18/106 (17%)
		C2H2 Zn finger	691..711	CDD:275368	5/45 (11%)
		C2H2 Zn finger	719..739	CDD:275368	10/19 (53%)
		zf-H2C2_2	731..756	CDD:290200	10/24 (42%)
		COG5048	742..>824	CDD:227381	21/81 (26%)
		C2H2 Zn finger	747..767	CDD:275368	6/19 (32%)
		zf-H2C2_2	763..784	CDD:290200	10/20 (50%)
		C2H2 Zn finger	775..795	CDD:275368	0/19 (0%)
		C2H2 Zn finger	803..818	CDD:275368	4/14 (29%)
		C2H2 Zn finger	831..851	CDD:275368	8/19 (42%)
		C2H2 Zn finger	859..877	CDD:275368
che-1	NP_001076598.1	zf-C2H2	166..188	CDD:278523	11/21 (52%)
		C2H2 Zn finger	168..188	CDD:275368	10/19 (53%)
		zf-H2C2_2	180..205	CDD:290200	10/24 (42%)
		C2H2 Zn finger	196..216	CDD:275368	6/19 (32%)
		zf-H2C2_2	208..232	CDD:290200	13/51 (25%)
		C2H2 Zn finger	224..244	CDD:275368	6/19 (32%)
		zf-H2C2_2	237..261	CDD:290200	6/23 (26%)
		C2H2 Zn finger	252..272	CDD:275368	8/19 (42%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000