DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Lnpk and LNP1

DIOPT Version :9

Sequence 1:	NP_001286201.1	Gene:	Lnpk / 35842	FlyBaseID:	FBgn0033309	Length:	387	Species:	Drosophila melanogaster
Sequence 2:	NP_012062.1	Gene:	LNP1 / 856599	SGDID:	S000001235	Length:	278	Species:	Saccharomyces cerevisiae

Alignment Length:	348	Identity:	60/348 - (17%)
Similarity:	117/348 - (33%)	Gaps:	122/348 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 AVLEGLQTQIQALEKYMINTEERKRRFVTN--FVGFTIGAYIVGFGLWWYFYFPPTMQECFMYLV 78
            |.|..:.:||..|:..:..::....::.:|  |.|..:....:.:..|.|..:.|     ::.:.
Yeast    24 ADLSQITSQIHQLDVALKKSQSILSQWQSNLTFYGIALTVLALSYTYWEYHGYRP-----YLVVT 83

  Fly    79 PLLLFPIVIIF---LRRLFTWYFQRKLNKNGDKLTRLKEDKRKILEQVMDKETYKVAVNLLERFG 140
            .||....:|:|   |.:|:.:|...:|.    ||.:|:...:|.||::.::..|....::::||
Yeast    84 ALLCIGSLILFKWALTKLYAFYNNNRLR----KLAKLRAIHQKKLEKLKEETHYNATSSIIQRF- 143

  Fly   141 DKKQLRISGLPTGSTPNRPQVERSPLTVAAVARTSSAGGQQQQQRSL--------APYTSVYRNN 197
                                                :.|:.|...::        |.|..:
Yeast   144 ------------------------------------SSGEDQNDDAMVLLDDELNAKYQEL---- 168

  Fly   198 NNNQNTSLNSSVISTHSLGQMTSASPQLRAVQELRRRSPFPIVDDRSRSAIDRIVDFIVGDSPKD 262
             ||..|.|......:|              |:.|::        :.|.:..|:|:..:.|.:..|
Yeast   169 -NNLKTELEKFKKESH--------------VKGLKK--------EDSDAWFDKIISVLAGGNELD 210

  Fly   263 RFG-------MICKACHAHNGMLPKEEYEYTT----FRCAFCNVLNPARKKRPVAPRLSLEAPSD 316
            ...       :||..||..:..     |...:    |.|..||                  ...|
Yeast   211 STSSLSPFKKIICPQCHWKSNC-----YRLASKPIIFICPHCN------------------HKID 252

  Fly   317 TANKRNDSSESE--SSDDDSDKE 337
            ...:|.|:.|::  :....|:||
Yeast   253 EVKEREDAIEAKQPAQPSQSEKE 275

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Lnpk	NP_001286201.1	zinc_ribbon_10	247..297	CDD:287076	13/60 (22%)
LNP1	NP_012062.1	COG5415	10..278	CDD:227702	60/348 (17%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2846
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR22166
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000