Protein Alignment Lnpk and LNPK

DIOPT Version :9

• Sequence 1: NP_001286201.1
• Gene: Lnpk / 35842
• FlyBaseID: FBgn0033309
• Length: 387
• Species: Drosophila melanogaster
• Sequence 2: NP_001291937.1
• Gene: LNPK / 80856
• HGNCID: 21610
• Length: 494
• Species: Homo sapiens
• Alignment Length: 446
• Identity: 136/446 - (30%)
• Similarity: 216/446 - (48%)
• Gaps: 94/446 - (21%)

  Fly     2 GFVLSKL--RKEKSTEAVLEGLQTQIQALEKYMINTEERKRRFVTNFVGFTIGAYIVGFGLWWYF 64
            |:::..:  :.:.||..|||.:..:|||||::....:..::.:|...:.::...|:....:.:.:
Human    66 GWIIFSMEGKTKPSTVEVLESIDKEIQALEEFREKNQRLQKLWVGRLILYSSVLYLFTCLIVYLW 130

  Fly    65 YFPPTMQECFMYLVPLLLFPIVIIFLRRLFTWYFQRKLNKNGDKLTRLKEDKRKILEQVMDKETY 129
            |.|..........:|...||::|..:|.:..::|.::..:|.:.|..||..::||||:||:||||
Human   131 YLPDEFTARLAMTLPFFAFPLIIWSIRTVIIFFFSKRTERNNEALDDLKSQRKKILEEVMEKETY 195

  Fly   130 KVAVNLLERFG-DKK----------------------------QLRISGLPTGSTPNR---PQVE 162
            |.|..:||||. |.|                            |..:|  ||.::||:   |||.
Human   196 KTAKLILERFDPDSKKAKECEPPSAGAAVTARPGQEIRQRTAAQRNLS--PTPASPNQGPPPQVP 258

  Fly   163 RSPLTVAAVARTSSAGGQQQQQRSLAPYTSVYRNNNNNQNTSLNSSVISTHSLGQMTSASPQLRA 227
            .||    ...:.|||.| ...:|::.|              :|:|:|:..| ||...::.|.:
Human   259 VSP----GPPKDSSAPG-GPPERTVTP--------------ALSSNVLPRH-LGSPATSVPGM-- 301

  Fly   228 VQELRRRSP---FPIVDDRSRSAIDRIVDFIVGDSPKDRFGMICKACHAHNGMLPKEEYEYTTFR 289
              .|....|   .||: .|.|.|:||||:::|||.|::|:.:||:.|.:||||..|||:||..||
Human   302 --GLHPPGPPLARPIL-PRERGALDRIVEYLVGDGPQNRYALICQQCFSHNGMALKEEFEYIAFR 363

  Fly   290 CAFCNVLNPARKKRPVAPRL---SLE-------------APSDTA----NKRNDSS-ESESSDDD 333
            ||:|..||||||.||.||||   |.|             .||.:.    |:.|:.| |.:..||:
Human   364 CAYCFFLNPARKTRPQAPRLPEFSFEKRQVVEGSSSVGPLPSGSVLSSDNQFNEESLEHDVLDDN 428

  Fly   334 S----DKEPSARRA--LLQKLPSGGADMDATAETEDLAMETETIETGSAAPSTAEV 383
            :    ||.|:..:.  :::| .|...:.:...|||:  .|...|||.|..|....:
Human   429 TEQTDDKIPATEQTNQVIEK-ASDSEEPEEKQETEN--EEASVIETNSTVPGADSI 481

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lnpk	NP_001286201.1	zinc_ribbon_10	247..297	CDD:287076	27/49 (55%)
LNPK	NP_001291937.1	PHA03247	<216..317	CDD:223021	28/127 (22%)
		zinc_ribbon_10	321..371	CDD:370800	27/49 (55%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165158199
Domainoid	1	1.000	86	1.000	Domainoid score	I8137
eggNOG	1	0.900	-	-		E1_KOG2846
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H12319
Inparanoid	1	1.050	171	1.000	Inparanoid score	I4113
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55649
OrthoDB	1	1.010	-	-		D1595535at2759
OrthoFinder	1	1.000	-	-		FOG0003331
OrthoInspector	1	1.000	-	-		oto91394
orthoMCL	1	0.900	-	-		OOG6_104219
Panther	1	1.100	-	-	LDO	PTHR22166
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R8618
SonicParanoid	1	1.000	-	-		X3815
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	16	15.800