DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp6a13 and CYP86A7

DIOPT Version :9

Sequence 1:	NP_610390.1	Gene:	Cyp6a13 / 35837	FlyBaseID:	FBgn0033304	Length:	493	Species:	Drosophila melanogaster
Sequence 2:	NP_176558.1	Gene:	CYP86A7 / 842675	AraportID:	AT1G63710	Length:	523	Species:	Arabidopsis thaliana

Alignment Length:	532	Identity:	125/532 - (23%)
Similarity:	224/532 - (42%)	Gaps:	79/532 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MLTLLVLVFTVGLLLYVKLRWHYSYWSRRGVAGERPVYFRGNMSGLGRDLHWTDINLRIYRKFRG 65
            :|||:|..    ::.:|.|        ||...|.|.....|::..|..:.|      |::.....
plant     9 ILTLIVTY----IIWFVSL--------RRSYKGPRVWPLVGSLPALITNAH------RMHDFIAD 55

  Fly    66 VERYCG--YFT------FMTKS----LFIMDLELIRDIMIRDFSSFADRGLFHNVRDDPLTGNLL 118
            ..|.||  |.|      |:.|.    ....|.:.:..|:...|.::.....:.:|..|.|...:.
plant    56 NLRMCGGTYQTCIFPIPFLAKKQGHVTVTCDPKNLEHILKTRFDNYPKGPSWQSVFHDLLGDGIF 120

  Fly   119 FLDGPEWRWLRQNLTQVFTSGKMKFMFPNMVEVGEK-----LTQACRLQVGEIEAKDLCARFTTD 178
            ..||..||:.|:.....||:..::......|:...|     :.::.|.:...|:.:|:..|.|.|
plant   121 NSDGDTWRFQRKTAALEFTTRTLRQAMARWVDRAIKNRLVPILESARSRAEPIDLQDVLLRLTFD 185

  Fly   179 VIGSCAFGLECNSLQDPES---QFRRMGRSVTQEPLHSVLVQAFMFAQPELARKLR--FRLFRPE 238
            .|....||      :||.:   :|...|.:|..:......:|.|:  .||...|:|  .||...:
plant   186 NICGLTFG------KDPRTLSPEFPENGFAVAFDGATEATLQRFI--MPEFIWKIRKWLRLGLED 242

  Fly   239 ------------VSEFFLDTVRQTLDYRRRENIHRNDLIQLLMELGEEGVKDALSFEQIAAQALV 291
                        :||.......:.|..::.|:.| :||:...|:     .|::.|.:.:...||.
plant   243 DMSRSISHVDNYLSEIINTRKLELLGQQQDESRH-DDLLSRFMK-----KKESYSDKYLKYVALN 301

  Fly   292 FFLAGFDTSSTTMSFCLYELALNPDVQERLRVEVLAVL---------KRNNQKLTYDSVQEMPYL 347
            |.|||.||||..||:..:.::|||.|:|::..|:..:|         |..::.||:|.:.::.||
plant   302 FILAGRDTSSVAMSWFFWLVSLNPRVEEKIINEICTILIKTRDTNVSKWTDEPLTFDEIDQLVYL 366

  Fly   348 DQVVAETLRKYPILPHLLRRSTKEYQIPNSNLILEPGSKIIIPVHSIHHDPELY-PDPEKFDPSR 411
            ...::||||.||.:|...:.......:|:...: ..||.:...::|:.....:: .|..:|.|.|
plant   367 KAALSETLRLYPSVPEDSKFVVANDVLPDGTFV-PSGSNVTYSIYSVGRMKFIWGEDCLEFKPER 430

  Fly   412 F-EPEEIKARHPFAYLPFGEGPRNCIGERFGKLQVKVGLVYLLRDFKFSRSEKTQIPLKFSSRNF 475
            : |....:..:.:.::.|..|||.|:|:....||:|.....:|...:.:.:...::..|.|...|
plant   431 WLEESRDEKCNQYKFVAFNAGPRICLGKDLAYLQMKSITASILLRHRLTVAPGHRVEQKMSLTLF 495

  Fly   476 L-ISTQEGVHLR 486
            : ...:..||.|
plant   496 MKFGLKMDVHKR 507

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a13	NP_610390.1	p450	33..476	CDD:278495	113/487 (23%)
CYP86A7	NP_176558.1	PLN03195	4..507	CDD:215627	124/530 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000