DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp6a13 and CYP96A12

DIOPT Version :9

Sequence 1:	NP_610390.1	Gene:	Cyp6a13 / 35837	FlyBaseID:	FBgn0033304	Length:	493	Species:	Drosophila melanogaster
Sequence 2:	NP_195661.1	Gene:	CYP96A12 / 830105	AraportID:	AT4G39510	Length:	508	Species:	Arabidopsis thaliana

Alignment Length:	544	Identity:	126/544 - (23%)
Similarity:	217/544 - (39%)	Gaps:	113/544 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 VLVFTVGLLLYVKLRWHYSYWSR-RG-VAGERPVYFRGNMSGLGRDLHWTDINLRIYRKFRGVER 68
            |.:..|.:.:.....::|.|:.: .| |....||.  |.:.|....||      |||.  .|||.
plant     4 VSLLDVAIAIICLFFFYYMYFKKPHGQVFRNWPVI--GMLPGFLMVLH------RIYN--FGVEA 58

  Fly    69 Y-CGYFTFMTKS--------LFIMDLELIRDIMIRDFSSFADRGLFHNVRDDPLTGNLLFLDGPE 124
            . ..:.||:.|.        ||.:|...|..|:..:||::.....|..|.|  :.|.::|....|
plant    59 LEMSHLTFLFKGPWFAEMDMLFTVDPANIHYILSSNFSNYTKGADFKEVFD--VFGEMIFSSDSE 121

  Fly   125 WRWLRQNLTQVFTSGKMKFMFPNMVEVGEKL--------TQACRLQVGEIEAKDLCARFTTDVIG 181
             .|..|.....|......|...::.....||        .|.|. :...::.:.:..|||.|...
plant   122 -LWKNQRKAAQFMLNHQGFQKLSLSATRSKLYDGLVPLFNQCCE-EEKVVDLQQVFQRFTFDTTF 184

  Fly   182 SCAFGLECNSL--QDPESQFRR----MGRSVTQEPLHSVLVQAFMFAQPELARKL--RFRL---F 235
            ....|.:..||  :.||.::.:    :|..:           .:...:|:...||  ||.|   .
plant   185 FIVTGFDPKSLSIEMPEVEYAKALDDLGEGI-----------FYRHIKPKFFWKLQNRFGLGQEK 238

  Fly   236 RPEVSEFFLDTVRQTLDYRRRENI-------HRN----DLI-----------QLLMELGEEGVKD 278
            |...::...|.|.......:||.|       |.|    ||:           :||....::.::|
plant   239 RMTEADATFDRVSAKYILAKREEIRSQGIDHHANGESEDLLTSHIKLDTTKYELLNPSDDKFLRD 303

  Fly   279 ALSFEQIAAQALVFFLAGFDTSSTTMSFCLYELALNPDVQERLRVEVL--AVLK--RNNQKLTYD 339
            .:         |.|.|||.||:|:.:|:..:.|:.||.|..::|.|::  .:.|  ||.|    :
plant   304 TI---------LAFNLAGRDTTSSALSWFFWLLSENPQVVTKIRKEIIDKNISKDGRNGQ----E 355

  Fly   340 SVQEMPYLDQVVAETLRKYPILPHLLRRSTKEYQIPNSNLILEPGSKIIIPVHSIHHDPELY-PD 403
            ::.::.||...:.|::|.||.:....:...|...:|:.:.: |..|.|||.:.::.....:: .|
plant   356 NLDKLVYLHAALYESMRLYPPVAFQRKSPIKPDVLPSGHKV-EANSVIIIFLFALGRMRAVWGED 419

  Fly   404 PEKFDPSRFEPEEIKARH--PFAYLPFGEGPRNCIGERFGKLQVKVGLVYLLRDFKFS--RSEKT 464
            ..:|.|.|:..|....||  .|.:|.|..|||.|.|::.....:|..:|.:|:::...  :.:|
plant   420 ATEFKPERWVSESGGLRHAPSFKFLSFNAGPRTCPGKQLAMTLMKTVVVEILQNYDIDVIKGQK- 483

  Fly   465 QIPLKFSSRNFLISTQEGVHLRME 488
                        |..:.|:.|.|:
plant   484 ------------IEPEPGLMLHMK 495

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a13	NP_610390.1	p450	33..476	CDD:278495	116/501 (23%)
CYP96A12	NP_195661.1	CYP86A	66..498	CDD:410687	107/472 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000