DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp6a13 and CYP72A14

DIOPT Version :9

Sequence 1:	NP_610390.1	Gene:	Cyp6a13 / 35837	FlyBaseID:	FBgn0033304	Length:	493	Species:	Drosophila melanogaster
Sequence 2:	NP_188086.1	Gene:	CYP72A14 / 820696	AraportID:	AT3G14680	Length:	512	Species:	Arabidopsis thaliana

Alignment Length:	446	Identity:	122/446 - (27%)
Similarity:	197/446 - (44%)	Gaps:	72/446 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    79 SLFIMDLELIRDIMIRDFSSFADRGLFHNVRDDPL-----TGNLLFLDGPEWRWLRQNLTQVFTS 138
            ::.|||.|.|:::    |:...|   |......||     || |:..||.:|...|:.:...|..
plant   105 TITIMDPEQIKEV----FNKVYD---FQKAHTFPLSKILGTG-LVSYDGDKWAQHRRIINPAFHL 161

  Fly   139 GKMKFMFPNMVEVGEKLTQACRLQVG-------------EIEAKDLCARFTTDVIGSCAFGLECN 190
            .|:|    |||.|   ..::|...||             |::........|.|||...|||
plant   162 EKIK----NMVHV---FHESCSELVGEWDKLVSDKGSSCEVDVWPGLTSMTADVISRTAFG---- 215

  Fly   191 SLQDPESQFRRMGRSV--TQEPLHSVLVQAFM-FAQP---ELARK--LRFRLFRPEVSEFFLDTV 247
                  |.:|. |..:  .|..|..:::|||. |..|   .|..|  .|.:....|:.:.....:
plant   216 ------SSYRE-GHRIFELQAELAQLVMQAFQKFFIPGYIYLPTKGNRRMKTAAREIQDILRGII 273

  Fly   248 RQTLDYRRRENIHRNDLIQLLME--LGE-EGVKDALSFEQIAAQALVFFLAGFDTSSTTMSFCLY 309
            .:....|........||:.:|:|  ||: ||  :.:|.|.:..:..:|:|||.:|:|..:.:.:.
plant   274 NKRERARESGEAPSEDLLGILLESNLGQTEG--NGMSTEDMMEECKLFYLAGQETTSVLLVWTMV 336

  Fly   310 ELALNPDVQERLRVEVLAVLKRNNQKLTYDSVQEMPYLDQVVAETLRKYPILPHLLRRSTKEYQI 374
            .|:.:.|.|.|.|.||..|.  .:::...:.:.::..:..::.|.||.||.:..|.|...||.::
plant   337 LLSQHQDWQARAREEVKQVF--GDKQPDTEGLNQLKVMTMILYEVLRLYPPVVQLTRAIHKEMKL 399

  Fly   375 PNSNLILEPGSKIIIPVHSIHHDPELY-PDPEKFDPSRFEPEEIKA-RHPFAYLPFGEGPRNCIG 437
              .:|.|..|.:|.:||..:|.|.||: .|..:|.|.||:....|| ::..::.||..|||.|||
plant   400 --GDLTLPGGVQISLPVLLVHRDTELWGNDAGEFKPERFKDGLSKATKNQVSFFPFAWGPRICIG 462

  Fly   438 ERFGKLQVKVGLVYLLRDFKFSRSEKTQIPLKFSSRNFLIST---QEGVHLRMEGL 490
            :.|..|:.|:.:..:|:.|.|..|.      .:....:.|.|   |.|.||.:..|
plant   463 QNFTLLEAKMAMSLILQRFSFELSP------SYVHAPYTIITLYPQFGAHLMLHKL 512

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a13	NP_610390.1	p450	33..476	CDD:278495	115/427 (27%)
CYP72A14	NP_188086.1	p450	24..512	CDD:299894	121/444 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm3438
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.900