DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp6a13 and CYP709B1

DIOPT Version :9

Sequence 1:	NP_610390.1	Gene:	Cyp6a13 / 35837	FlyBaseID:	FBgn0033304	Length:	493	Species:	Drosophila melanogaster
Sequence 2:	NP_566092.1	Gene:	CYP709B1 / 819310	AraportID:	AT2G46960	Length:	519	Species:	Arabidopsis thaliana

Alignment Length:	546	Identity:	139/546 - (25%)
Similarity:	252/546 - (46%)	Gaps:	90/546 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 LTLLVLVFTVGLLL---YVKLRWHYSYWSRR----GVAGERPVYFRGNMS---GLGRDLHWT--- 53
            |.|:||:..:||.:   ::.|.||....:||    |::|.....|.||:|   .:.|:.|.:
plant     7 LALIVLILIIGLRIFKAFMILVWHPFVLTRRLKNQGISGPNYRIFYGNLSEIKKMKRESHLSILD 71

  Fly    54 ----DINLRI---YRKFRGVERYCGYFTFMTKS---LFIMDLELIRDIMIRDFSSFADRGLFHNV 108
                ||..||   |:|:  :.:|...|.:...:   :.|.|.||.:.::....      |.|...
plant    72 PSSNDIFPRILPHYQKW--MSQYGETFLYWNGTEPRICISDPELAKTMLSNKL------GFFVKS 128

  Fly   109 RDDP----LTGN--LLFLDGPEWRWLRQNLTQVFTSGKMKFMFPNMVEVGEKLTQACRLQVGEIE 167
            :..|    |.|:  |:|::|.:|...|:.|...|:..::|.|...||:...|:.:..|.:..:.|
plant   129 KARPEAVKLVGSKGLVFIEGADWVRHRRILNPAFSIDRLKIMTTVMVDCTLKMLEEWRKESTKEE 193

  Fly   168 AK---------DLCARFTTDVIGSCAFGLECNSLQDPESQFR---RMGRSVTQEPLHSVLVQAFM 220
            .:         :...|.|.|:|.:.|||   :|..:....||   .:.|..|.. |:.|.:....
plant   194 TEHPKIKKEMNEEFQRLTADIIATSAFG---SSYVEGIEVFRSQMELKRCYTTS-LNQVSIPGTQ 254

  Fly   221 FAQP-------ELARKLRFRLFRPEVSEFFLDTVRQTLDYR-RRENIHRNDLIQLLME-LGEEGV 276
            :...       :|.||:.             :::::.:..| :.::.:.:||:.:|:: ...||.
plant   255 YLPTPSNIRVWKLERKMD-------------NSIKRIISSRLQSKSDYGDDLLGILLKAYNTEGK 306

  Fly   277 KDALSFEQIAAQALVFFLAGFDTSSTTMSFCLYELALNPDVQERLRVEVLAVLKRNNQKLTYDS- 340
            :..:|.|:|..:...||..|.:|:|..:::....|:|:.|.||:||.|   :.|...::.|.||
plant   307 ERKMSIEEIIHECRTFFFGGHETTSNLLAWTTMLLSLHQDWQEKLREE---IFKECGKEKTPDSE 368

  Fly   341 -VQEMPYLDQVVAETLRKYPILPHLLRRSTKEYQIPNSNLILEPGSKIIIPVHSIHHDPELY-PD 403
             ..::..::.|:.|:||.|..:..|.|.::...::  .:|.:..|:.::||:..:|.|..|: .|
plant   369 TFSKLKLMNMVIMESLRLYGPVSALAREASVNIKL--GDLEIPKGTTVVIPLLKMHSDKTLWGSD 431

  Fly   404 PEKFDPSRFEPEEIK-ARHPFAYLPFGEGPRNCIGERFGKLQVKVGLVYLLRDFKFSR--SEKTQ 465
            .:||:|.||.....: |.||.|.|.|..|||.|||:.|..::.|..|..:|:.|:|..  .|...
plant   432 ADKFNPMRFANGVSRAANHPNALLAFSVGPRACIGQNFVMIEAKTVLTMILQRFRFISLCDEYKH 496

  Fly   466 IPLKFSSRNFLISTQEGVHLRMEGLE 491
            .|:.    |..|..|.|:.:.::.||
plant   497 TPVD----NVTIQPQYGLPVMLQPLE 518

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a13	NP_610390.1	p450	33..476	CDD:278495	122/491 (25%)
CYP709B1	NP_566092.1	p450	32..517	CDD:299894	128/518 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm3438
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810