Protein Alignment Cyp6a13 and Cyp46a1

DIOPT Version :10

• Sequence 1: NP_610390.1
• Gene: Cyp6a13 / 35837
• FlyBaseID: FBgn0033304
• Length: 493
• Species: Drosophila melanogaster
• Sequence 2: NP_001386630.1
• Gene: Cyp46a1 / 362782
• RGDID: 1306605
• Length: 500
• Species: Rattus norvegicus
• Alignment Length: 452
• Identity: 120/452 - (26%)
• Similarity: 208/452 - (46%)
• Gaps: 57/452 - (12%)

  Fly    35 RPVYFRGNM-------SGLGRDLHWTDINLRIYRKFRGVERYCGYFTFMTKSLFIMDLELIRDIM 92
            ||.:..|::       ...||.|.  |:.|...:|:..|.|   ...|...|:.:...|.::..:
  Rat    38 RPSFLLGHLPYFWKKDEACGRVLQ--DVFLDWAKKYGPVVR---VNVFHKTSVIVTSPESVKKFL 97

  Fly    93 I-----RDFSSFADRGLFHNVRDDPLTGNLLFLDGPEWRWLRQN--LTQVFTSGKMKFMFPNMVE 150
            :     :|...:.   ....|..:.|.|..|..:....||.:|.  :...|:...:..:.....|
  Rat    98 MSTKYNKDSKMYR---AIQTVFGERLFGQGLVSECDYGRWYKQRRVMDLAFSRSSLVSLMGTFNE 159

  Fly   151 VGEKLTQACRLQV-GE--IEAKDLCARFTTDVIGSCAFGLECNSL---QDPESQFRRM---GRSV 206
            ..|:|.:....:. |:  :..:|:....|.|::...|||:|.:.|   |.|.||..::   |.|.
  Rat   160 KAEQLMEILEAKADGQTPVSMQDMLTCATIDILAKAAFGMETSMLLGAQKPLSQAVKVMLEGISA 224

  Fly   207 TQEPLHSVLVQAFMFAQPELARKLR--FRLFRPEVSEFFLDTVRQTLDYRRRENIHRNDLIQLLM 269
            ::..|     ..||..:.:..|::|  .||.| :|.:.::...|:.|  :|.|::..:.|.|:|.
  Rat   225 SRNTL-----AKFMPGKRKQLREIRESIRLLR-QVGKDWVQRRREAL--KRGEDVPADILTQILK 281

  Fly   270 ELGEEGVKDALSFEQIAAQALVFFLAGFDTSSTTMSFCLYELALNPDVQERLRVEVLAVL--KRN 332
              .|||.:|.   |.:....:.||:||.:||:..::|.:.||:..|::..||:.||..|:  ||:
  Rat   282 --AEEGAQDD---EVLLDNFVTFFIAGHETSANHLAFTVMELSRQPEIVARLQAEVDEVVGSKRH 341

  Fly   333 NQKLTYDSVQEMPYLDQVVAETLRKYPILPHLLRRSTKEYQIPNSNLILEPG-SKIIIPVHSIHH 396
               |.|:.:..:.||.||:.|:||.||......|...:|..|..   :..|| :.::...:.:..
  Rat   342 ---LDYEDLGRLQYLSQVLKESLRLYPPAWGTFRLLEEETLIDG---VRVPGNTPLLFSTYVMGR 400

  Fly   397 DPELYPDPEKFDPSRFEPEEIKARHPFAYLPFGEGPRNCIGERFGKLQVKVGLVYLLRDFKF 458
            ....:.||..|:|.||.|...|.|  |.|.||..|.|:|||::|.:::|||.:..||:..:|
  Rat   401 MDTYFEDPLTFNPDRFGPGAPKPR--FTYFPFSLGHRSCIGQQFAQMEVKVVMAKLLQRLEF 460

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a13	NP_610390.1	CYP6-like	67..484	CDD:410679	110/413 (27%)
Cyp46a1	NP_001386630.1	CYP46A1-like	61..484	CDD:410706	114/429 (27%)