Protein Alignment Cyp6a13 and CYP4V2

DIOPT Version :10

• Sequence 1: NP_610390.1
• Gene: Cyp6a13 / 35837
• FlyBaseID: FBgn0033304
• Length: 493
• Species: Drosophila melanogaster
• Sequence 2: NP_997235.3
• Gene: CYP4V2 / 285440
• HGNCID: 23198
• Length: 525
• Species: Homo sapiens
• Alignment Length: 385
• Identity: 103/385 - (26%)
• Similarity: 185/385 - (48%)
• Gaps: 45/385 - (11%)

  Fly   111 DPLTG-NLLFLDGPEWRWLRQNLTQVFTSGKMKFMFPNMVEVGEKLTQACRLQVGEIEAKD---- 170
            :|..| .||...|.:||..|:.||..|....::.....|.|....|.:.....:.: ||.:
Human   128 EPWLGLGLLTSTGNKWRSRRKMLTPTFHFTILEDFLDIMNEQANILVKKLEKHINQ-EAFNCFFY 191

  Fly   171 --LCARFTTDVIGSCAFGLECNSLQDPESQFRRMGRSVTQEPLHSVLVQAFMFAQPELARKLRFR 233
              |||   .|:|...|.|....:..:.:|::.|....:::.....:       ..|.|...|.:.
Human   192 ITLCA---LDIICETAMGKNIGAQSNDDSEYVRAVYRMSEMIFRRI-------KMPWLWLDLWYL 246

  Fly   234 LFRP----EVSEFFLDTVRQTLDYRRRENIHRND------------------LIQLLMEL-GEEG 275
            :|:.    :.|...|.|...::...|...::.|:                  .:.||:.: .:||
Human   247 MFKEGWEHKKSLQILHTFTNSVIAERANEMNANEDCRGDGRGSAPSKNKRRAFLDLLLSVTDDEG 311

  Fly   276 VKDALSFEQIAAQALVFFLAGFDTSSTTMSFCLYELALNPDVQERLRVEVLAVLKRNNQKLTYDS 340
              :.||.|.|..:...|...|.||::..:::.||.|..||:||:::..|:..|..::::..|.:.
Human   312 --NRLSHEDIREEVDTFMFEGHDTTAAAINWSLYLLGSNPEVQKKVDHELDDVFGKSDRPATVED 374

  Fly   341 VQEMPYLDQVVAETLRKYPILPHLLRRSTKEYQIPNSNLILEPGSKIIIPVHSIHHDPELYPDPE 405
            ::::.||:.|:.||||.:|.:|...|..:::.::.... :|:....:||| :::|.||..:|:||
Human   375 LKKLRYLECVIKETLRLFPSVPLFARSVSEDCEVAGYR-VLKGTEAVIIP-YALHRDPRYFPNPE 437

  Fly   406 KFDPSRFEPEEIKARHPFAYLPFGEGPRNCIGERFGKLQVKVGLVYLLRDFKFSRSEKTQ 465
            :|.|.||.||..:.|||:||:||..|||||||::|..::.|..|..:||.|....::|.:
Human   438 EFQPERFFPENAQGRHPYAYVPFSAGPRNCIGQKFAVMEEKTILSCILRHFWIESNQKRE 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a13	NP_610390.1	CYP6-like	67..484	CDD:410679	103/385 (27%)
CYP4V2	NP_997235.3	CYP4V	76..515	CDD:410773	103/385 (27%)