Protein Alignment Cyp6a13 and cyp-13A8

DIOPT Version :10

• Sequence 1: NP_610390.1
• Gene: Cyp6a13 / 35837
• FlyBaseID: FBgn0033304
• Length: 493
• Species: Drosophila melanogaster
• Sequence 2: NP_496115.1
• Gene: cyp-13A8 / 188358
• WormBaseID: WBGene00011674
• Length: 509
• Species: Caenorhabditis elegans
• Alignment Length: 554
• Identity: 145/554 - (26%)
• Similarity: 248/554 - (44%)
• Gaps: 116/554 - (20%)

  Fly     1 MLTLLVLVFTVGLLLYVKLRWHYSYWSRRGVAGERPVYFRGNMSGLGRD--------LHWTDINL 57
            |:..|:|:..|....     ||:::|.|||:.|...|...|....:..|        ..||....
 Worm     1 MIFELILISIVTYYF-----WHWTFWKRRGLPGPWGVPIFGKAGAMLEDSFPPGYTLQKWTKEYG 60

  Fly    58 RIYRKFRGVERYCGYFTFMTKSLFIMDLELIRDIMIRDFSSFADRGLFHN-VRDDPLTGNLLFLD 121
            :||          |:...|.|.:.|.|.:|:::|:::.:.:|..|.  || |:.||.....:.:.
 Worm    61 KIY----------GFTEGMQKVMVISDPDLVQEILVKQYDNFYGRK--HNPVQGDPDKDKDIHIV 113

  Fly   122 GPE---WRWLRQNLTQVFTSGKMKFMFPNMVEVGEKLTQACRLQVGEIEAKDL---CARFTTDVI 180
            |.:   |:.||......|::|.:|.:...|.:..::|.:..|.:....:|.::   ...:|.|||
 Worm   114 GAQGFRWKRLRTITAPAFSNGSIKKVLTTMEDSTQELMKKLREESENGKAVNMHLFYQEYTFDVI 178

  Fly   181 GSCAFGLECNSLQDPESQFRRMGRSVTQEPL---------HSVLVQAFMFAQ--PELARKLRFRL 234
            ...|.|       .|:||       :.:.||         |: ..|.:||:.  |.....|::..
 Worm   179 SRVAMG-------QPDSQ-------MFKNPLLKDVKGFFEHN-RWQIWMFSGGFPFAVSFLKWLF 228

  Fly   235 FRPEVSEF----FL-------DTVRQTLDYRRRENIH------RNDLIQLLM----------ELG 272
            .:  |.:|    |:       |.|...:..|..:..|      ..|.|.:.:          |..
 Worm   229 IK--VGKFGAGPFIVVQKSVTDAVMSRIAQREADKKHGVEPGEAADYIDMFLNARAEVEHFGESN 291

  Fly   273 EEGVKDA------LSFEQIAAQALVFFLAGFDTSSTTMSFCLYELALNPDVQERLRVEVLAVLKR 331
            :|..|.:      |:.::|.:|..||.:|||||::.::|:..|.|||||.:|.:|:.||  ..:.
 Worm   292 DEFHKSSSYNNRQLTTQEIISQCFVFLVAGFDTTAISLSYVTYFLALNPKIQSKLQDEV--DKEC 354

  Fly   332 NNQKLTYDSVQEMPYLDQVVAETLRKYPILPHL-LRRSTKEYQIPNSNLILEPGSKIIIPVHSIH 395
            .|.::|:|.:.::.|:|.|:.|:||.:|..... .||..:...|  ...|:|.|..::|...::|
 Worm   355 PNDEITFDQLSKLKYMDNVIKESLRLFPFASFANSRRCMRNTVI--GEQIVEAGVDVMIDTWTLH 417

  Fly   396 HDPELY-PDPEKFDPSRFE----PEEIKARHPFAYLPFGEGPRNCIGERFGKLQVKVGLVYLLRD 455
            ||..:: .|.|:|.|.|::    |::       |||.||.|||.|:|.||..|:.|..|.::|:.
 Worm   418 HDKNVWGNDVEEFKPERWDSPLTPQQ-------AYLSFGAGPRVCLGMRFALLEQKGLLSHILKK 475

  Fly   456 FKFSRSEKTQIPLKFSSR------NFLISTQEGV 483
            :.|..:.|||:|:|...|      |..:|.:..|
 Worm   476 YTFETNAKTQLPIKLVGRATARPENLFLSLKPRV 509

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a13	NP_610390.1	CYP6-like	67..484	CDD:410679	127/480 (26%)
cyp-13A8	NP_496115.1	CYP3A-like	58..500	CDD:410678	126/481 (26%)