Protein Alignment Cyp6a13 and cyp-13A6

DIOPT Version :10

• Sequence 1: NP_610390.1
• Gene: Cyp6a13 / 35837
• FlyBaseID: FBgn0033304
• Length: 493
• Species: Drosophila melanogaster
• Sequence 2: NP_496113.1
• Gene: cyp-13A6 / 188357
• WormBaseID: WBGene00011673
• Length: 518
• Species: Caenorhabditis elegans
• Alignment Length: 544
• Identity: 141/544 - (25%)
• Similarity: 250/544 - (45%)
• Gaps: 86/544 - (15%)

  Fly     1 MLTLLVLVFTVGLLLYVKLRWHYSYWSRRGVAGERPVYFRGNMSGLGRDLHWTDINLRIYRKFRG 65
            |:.:|:....:|:..|..  |.:||:.|:|:.|.|      ...|:|..:...|.....:.|:|.
 Worm     1 MIFVLLSAVLLGVFTYSV--WIWSYFIRKGIKGPR------GFPGIGMLIQTIDHENPPFLKYRD 57

  Fly    66 -VERYCGYFTFM---TKSLFIMDLELIRDIMIRDFSSFADRGLFHNVRDDPLTG--------NLL 118
             .::|...:.|.   .:::.|.:.|::.:|..:.|.:|..|.|      .|:.|        |:.
 Worm    58 WTKQYGPVYGFTEGPQQTMIISEPEMVNEIFKKQFDNFYGRKL------RPIIGDPEKDKRVNIF 116

  Fly   119 FLDGPEWRWLRQNLTQVFTSGKMKFMFPNMVEVGEKLTQACRLQVGEIEAKDLC---ARFTTDVI 180
            ...|..|:.||...:..|::..::.:..::.|.|.::......:|.:.|..|:.   ..:|..||
 Worm   117 STQGKRWKRLRTLSSPSFSNNSLRKVRNSVQECGTEILWNIEQKVRKNEDIDMLIVYQEYTLGVI 181

  Fly   181 GSCAFG-LECNSLQDPESQFRRMGRSVTQEPLHSVLVQAFMFAQPELA---RKLRFRL---FRPE 238
            ...|.| .|.|..::|   .....:::.....|..|:....   |.||   ||:...|   |.|.
 Worm   182 SRIALGQSESNMFKNP---LLPKVQAIFNGSWHVFLITGIF---PPLAGVFRKMSKMLPASFIPA 240

  Fly   239 VSEFFL--DTVRQTLDYRRRENI------HRNDLIQLLM------------ELGEEGVKDA---- 279
            ...|.|  ..|:..:|.|.::.|      ...|.|.|.:            |..|:..|.:
 Worm   241 FKIFDLIEVAVQARIDQRAKDEIKGVEPGEPQDFIDLFLDARVPDVKILSGEANEDFAKSSVVKI 305

  Fly   280 ---LSFEQIAAQALVFFLAGFDTSSTTMSFCLYELALNPDVQERLRVEVLAVLKRN--NQKLTYD 339
               |:|::|.||..||..|||||::.::|:..|.||.:|::|.:|:.||    .|.  :.::.:|
 Worm   306 NKELTFDEIIAQCFVFLAAGFDTTALSLSYATYLLATHPEIQTKLQEEV----DRECPDPEIFFD 366

  Fly   340 SVQEMPYLDQVVAETLRKYPI-LPHLLRRSTKEYQIPNSNLILEPGSKIIIPVHSIHHDPELY-P 402
            .:.::.||:.|:.||||.||: .....|:..:|..|...|  .:.|..|.:...::||:|.:: .
 Worm   367 HLSKLKYLECVMKETLRLYPLGTTANTRKCMRETTINGVN--FDEGMNIQVDTWTLHHNPRIWGE 429

  Fly   403 DPEKFDPSRFEP---EEIKARHPFAYLPFGEGPRNCIGERFGKLQVKVGLVYLLRDFKFSRSEKT 464
            |.|.|.|.|:|.   |.::  |..:|:|||.|||.|||.|..:::.|:.|..:|:::.|..::.|
 Worm   430 DVEDFKPERWENGACEHLE--HNGSYIPFGSGPRQCIGMRLAQMEQKILLAQILKEYSFRTTKNT 492

  Fly   465 QIPLKFSSRNFLISTQEGVHLRME 488
            |||:|...:  |..:.|.|.:::|
 Worm   493 QIPVKLVGK--LTLSPESVIVKLE 514

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a13	NP_610390.1	CYP6-like	67..484	CDD:410679	123/471 (26%)
cyp-13A6	NP_496113.1	CYP3A-like	61..511	CDD:410678	124/471 (26%)