Protein Alignment Cyp6a13 and cyp-13A4

DIOPT Version :10

• Sequence 1: NP_610390.1
• Gene: Cyp6a13 / 35837
• FlyBaseID: FBgn0033304
• Length: 493
• Species: Drosophila melanogaster
• Sequence 2: NP_496111.1
• Gene: cyp-13A4 / 188355
• WormBaseID: WBGene00011671
• Length: 520
• Species: Caenorhabditis elegans
• Alignment Length: 553
• Identity: 142/553 - (25%)
• Similarity: 249/553 - (45%)
• Gaps: 120/553 - (21%)

  Fly     2 LTLLVL-VFTVGLLLYVKLRWHYSYWSRRGVAGERPVYFRG--------NMSGLGRDLHWTDINL 57
            |:||:. ...:|.|.|  ..|.:|:|.|:||.|.|...|.|        ...||.:...||....
 Worm     3 LSLLIAGALFIGFLTY--YIWIWSFWIRKGVKGPRGFPFFGVILKFHDYENPGLLKLGEWTKKYG 65

  Fly    58 RIYRKFRGVERYCGYFTFMTKSLFIMDLELIRDIMIRDFSSFADRGLFHNVRDDPLTG------- 115
            .||....|||          |:|.:.:.|.:.::.::.|.:|..|      :.:|:.|
 Worm    66 SIYGITEGVE----------KTLVVSNPEFVHEVFVKQFDNFYGR------KTNPIQGDPNKNKR 114

  Fly   116 -NLLFLDGPEWRWLRQNLTQVFTSGKMKFMFPNMVEVGEKLTQACRLQVGEIEAK-------DLC 172
             :|:...|..|:.||...:..|::..::.:   |..|.|.:.:..| .:.|..||       |..
 Worm   115 AHLVLAQGHRWKRLRTLASPTFSNKSLRKI---MSTVEETVVELMR-HLDEASAKGKAVDLLDYY 175

  Fly   173 ARFTTDVIGSCAFG-LECNSLQDP-----ESQFRRMGRSVTQEPLHSVLVQAFMFAQPELARKL- 230
            ..||.|:||..|.| .|....::|     :..|::.|:      :..::...|..| ..|.|:|
 Worm   176 QEFTLDIIGRIAMGQTESLMFRNPMLPKVKEIFKKGGK------MPFLIAGVFPIA-GTLMRQLF 233

  Fly   231 -RFRLFRPEVSEFFLDTVRQTLDYRRRENI-----------HRNDLIQLLME-------LGEEG- 275
             :|..|.|...  .::|:.:.|:.|..:..           ...|.|.|.::       :.||.
 Worm   234 MKFPKFSPAFG--IMNTMEKALNKRLEQRAADKKAGIEPSGEPQDFIDLFLDARANVDFIEEEST 296

  Fly   276 ----------VKDALSFEQIAAQALVFFLAGFDTSSTTMSFCLYELALNPDVQERLRVEVLAVLK 330
                      |...|:|::|..|..||.|||:||::.::|:..|.||.:|::|::|:.||    .
 Worm   297 LGFAKSEVLKVDKHLTFDEIIGQLFVFLLAGYDTTALSLSYSSYLLATHPEIQKKLQEEV----D 357

  Fly   331 RN--NQKLTYDSVQEMPYLDQVVAETLRKYPILPHLLRRSTKEYQIPNSNLI---LEPGSKIIIP 390
            |.  :.::|:|.:.::.|::.||.|.||.||:...:..|..    :..:|::   ::.|:.:.:.
 Worm   358 RECPDPEVTFDQISKLKYMECVVKEALRMYPLASLVHNRKC----MKKTNVLGVEIDEGTNVQVD 418

  Fly   391 VHSIHHDPELYPDPEKFDPSRFEPEEIKARHPF-----AYLPFGEGPRNCIGERFGKLQVKVGLV 450
            ..::|:||:::.|    |.|.|:||..:.....     .|||||.|||.|||.|...::.|:.|.
 Worm   419 TWTLHYDPKVWGD----DASEFKPERWETGDELFYAKGGYLPFGMGPRICIGMRLAMMEEKLLLT 479

  Fly   451 YLLRDFKFSRSEKTQIPLK------FSSRNFLI 477
            ::|:.:.|..|.:|:||||      .:.||.::
 Worm   480 HILKKYTFDTSTETEIPLKLVGSATIAPRNVML 512

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a13	NP_610390.1	CYP6-like	67..484	CDD:410679	118/479 (25%)
cyp-13A4	NP_496111.1	CYP3A-like	63..511	CDD:410678	122/488 (25%)