Protein Alignment Cyp6a13 and cyp-25A1

DIOPT Version :10

• Sequence 1: NP_610390.1
• Gene: Cyp6a13 / 35837
• FlyBaseID: FBgn0033304
• Length: 493
• Species: Drosophila melanogaster
• Sequence 2: NP_497775.3
• Gene: cyp-25A1 / 183247
• WormBaseID: WBGene00007963
• Length: 502
• Species: Caenorhabditis elegans
• Alignment Length: 515
• Identity: 143/515 - (27%)
• Similarity: 241/515 - (46%)
• Gaps: 64/515 - (12%)

  Fly     3 TLLVLVFTVGLLLYVKLRWHYSYWSRRGVAGERPVYFRGNMSGLG---RDLHWTDINLRIYRKFR 64
            :|::.:||..:.:.:..|..:....:.|::|..|.:|.||:....   ..|.:.|.| |.:.:..
 Worm     8 SLVISIFTFFIYIILARRERFKLREKIGLSGPEPHWFLGNLKQTAERKEKLGYDDAN-RWFNELH 71

  Fly    65 GVERY---CGYFTFMTKSLFIMDLELIRDIMIRDFSSFADRGLFHNVRDDPLTGNLL---FLDGP 123
              |:|   .|.:.....::.|.:.:.|:::.|::||:|:||.:......:.||.:||   :..|
 Worm    72 --EQYGETFGIYYGSQMNIVISNEKDIKEVFIKNFSNFSDRSVPSIYEANQLTASLLMNSYSSG- 133

  Fly   124 EWRWLRQNLTQVFTSGKMKFMFPNMVEVGEKLTQACRLQVGEIEAKDLCARF---TTDVIGSCAF 185
             |:..|..:..:|::||||.|...:....:......|.:....:..|:...|   |.||||.|||
 Worm   134 -WKHTRSAIAPIFSTGKMKAMQETINSKVDLFLDILREKASSGQKWDIYDDFQGLTLDVIGKCAF 197

  Fly   186 GLECNSLQDPESQFRRMGRSVTQ--EPLHSVLVQAFMFAQPELARKLRFRLFRPEVSEFFLDTVR 248
            .::.|..:|....|....:....  :..||.::.|              .:..||:|.|:....:
 Worm   198 AIDSNCQRDRNDVFYVNAKKYISNIDIRHSKIIAA--------------SVLLPELSTFWKALYK 248

  Fly   249 QT--LD------------YRRR---ENIHRNDLIQLLMELGEEGVKDALSFEQIAAQALVFFLAG 296
            .|  .|            |.||   |.....||::||:. .|:.....::.:::......|.|||
 Worm   249 YTPLADAEIPLVEGLSNVYERRRGGEGSDSVDLLKLLLN-REDDKSKPMTKQEVIENCFAFLLAG 312

  Fly   297 FDTSSTTMSFCLYELALNPDVQERLRVEVLAVLKRNNQKLTYDSVQEMPYLDQVVAETLRKYPIL 361
            ::|:||.|::|.|.|:..|:||::|..|::..  :.|..|||||:..|.|||.|..||||.||.:
 Worm   313 YETTSTAMTYCSYLLSKYPNVQQKLYEEIMEA--KENGGLTYDSIHNMKYLDCVYKETLRFYPPV 375

  Fly   362 PHLLRRSTKEYQIPNSNLILEPGSKIIIPVHSIHHDPELYPDPEKFDPSRFEPEEIKARHPFAYL 426
            .|.:||..:| .|.........|:.::...|::|.:||.:..||:|.|.|||..|.|: ....::
 Worm   376 IHFIRRLCRE-DITIRGQFYPKGAIVVCLPHTVHRNPENWDSPEEFHPERFENWEEKS-SSLKWI 438

  Fly   427 PFGEGPRNCIGERFGKLQVKVGLVYLLRDFKFSRSEKTQIPLKFSSRNFLISTQEGVHLR 486
            |||.|||.|:|.||.:::.|..:|.||..|:..         :|.....||....||.:|
 Worm   439 PFGVGPRYCVGMRFAEMEFKTTIVKLLDTFELK---------QFEGEADLIPDCNGVIMR 489

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a13	NP_610390.1	CYP6-like	67..484	CDD:410679	127/444 (29%)
cyp-25A1	NP_497775.3	CYP3A-like	73..495	CDD:410678	128/447 (29%)