Protein Alignment Cyp6a13 and Cyp3a62

DIOPT Version :10

• Sequence 1: NP_610390.1
• Gene: Cyp6a13 / 35837
• FlyBaseID: FBgn0033304
• Length: 493
• Species: Drosophila melanogaster
• Sequence 2: NP_001019403.1
• Gene: Cyp3a62 / 170509
• RGDID: 1595919
• Length: 497
• Species: Rattus norvegicus
• Alignment Length: 495
• Identity: 154/495 - (31%)
• Similarity: 271/495 - (54%)
• Gaps: 50/495 - (10%)

  Fly     6 VLVFTVGLLLYVKLRWHYSYWSRRGVAGERPVYFRGNMSGLGRDLHWTDINLRIYRK-FRGVERY 69
            :|:.|:.:|||:.....:..:.:.|::|.:|:.|.|              |:..||. |...:|:
  Rat    13 MLLATILVLLYLYGTSTHGNFKKLGISGPKPLPFVG--------------NILAYRHGFWEFDRH 63

  Fly    70 C--------GYFTFMTKSLFIMDLELIRDIMIRD-FSSFADRGLFHNVRDDP---LTGNLLFLDG 122
            |        |::......|.|.|.::|:.::::: :|:|.:|..|     .|   |...:...:.
  Rat    64 CHKKYGDIWGFYEGRQPILAITDPDIIKTVLVKECYSTFTNRRSF-----GPAGILKKAITLSED 123

  Fly   123 PEWRWLRQNLTQVFTSGKMKFMFPNMVEVGEKLTQACRLQV---GEIEAKDLCARFTTDVIGSCA 184
            .||:.||..|:..|||||:|.|||.:.:..:.|.:..:.:.   ..|..||:...::.|||...:
  Rat   124 EEWKRLRTLLSPTFTSGKLKEMFPIINQYADLLVKNVKHEAEKGNPITMKDIFGAYSMDVITGTS 188

  Fly   185 FGLECNSLQDPESQFRRMGRSVTQ----EPLH-SVLVQAFMFAQPELARKLRFRLFRPEVSEFFL 244
            ||:..:||.:|::.|.:..:.:.:    :|.. ||::  |.|..| :.......:|..:|.:||.
  Rat   189 FGVNVDSLNNPQNPFVQKVKKLLKFNFLDPFFLSVIL--FPFLTP-VFEAFDITVFPKDVMKFFR 250

  Fly   245 DTVRQTLDYRRRENI-HRNDLIQLLMELGEEGVKDA---LSFEQIAAQALVFFLAGFDTSSTTMS 305
            .:|.:..:.|.:|.: .|.|.:||::.....|.|::   |:..:|.||::.|..||::|:|:.:|
  Rat   251 TSVERMKENRMQEKVKQRLDFLQLMINSQSSGDKESHQGLTDVEIVAQSIFFIFAGYETTSSALS 315

  Fly   306 FCLYELALNPDVQERLRVEVLAVLKRNNQKLTYDSVQEMPYLDQVVAETLRKYPILPHLLRRSTK 370
            |.||.||.:||:|::|:.|:.|.|. |...:|||.:.||.|||.|:.||||.:|:...|.|...|
  Rat   316 FALYLLATHPDLQKKLQDEIDAALP-NKAPVTYDVLVEMEYLDMVLNETLRLFPVGGRLERVCKK 379

  Fly   371 EYQIPNSNLILEPGSKIIIPVHSIHHDPELYPDPEKFDPSRFEPEEIKARHPFAYLPFGEGPRNC 435
            :.:|  :.:.:..|:.:::|..::|.||:.:|:||:|.|.||..:...:.:|:.|||||.|||||
  Rat   380 DVEI--NGVFIPKGTVVMVPTFALHKDPKCWPEPEEFCPERFRKKNQDSINPYIYLPFGNGPRNC 442

  Fly   436 IGERFGKLQVKVGLVYLLRDFKFSRSEKTQIPLKFSSRNF 475
            ||.||..:.:|:.||.:|::|.|...::||||||...:.|
  Rat   443 IGMRFALMNMKIALVRVLQNFSFGLCKETQIPLKLRKKGF 482

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a13	NP_610390.1	CYP6-like	67..484	CDD:410679	140/433 (32%)
Cyp3a62	NP_001019403.1	CYP3A	67..492	CDD:410743	138/427 (32%)