Protein Alignment Cyp6a13 and CYP27B1

DIOPT Version :10

• Sequence 1: NP_610390.1
• Gene: Cyp6a13 / 35837
• FlyBaseID: FBgn0033304
• Length: 493
• Species: Drosophila melanogaster
• Sequence 2: NP_000776.1
• Gene: CYP27B1 / 1594
• HGNCID: 2606
• Length: 508
• Species: Homo sapiens
• Alignment Length: 420
• Identity: 118/420 - (28%)
• Similarity: 178/420 - (42%)
• Gaps: 81/420 - (19%)

  Fly   117 LLFLDGPEWRWLRQNLTQVFTSGKMKFMFPNMV-EVGEKLTQACRLQVGEIEAKDLCARFTTDVI 180
            ||..:|.||:.||..|..:....:....:...: .|...|.:..|.|.|.........|   ||.
Human   126 LLTAEGEEWQRLRSLLAPLLLRPQAAARYAGTLNNVVCDLVRRLRRQRGRGTGPPALVR---DVA 187

  Fly   181 GS-CAFGLE------------CNSLQ---DPESQFRRMGRSVTQEPLHSVLVQAFM-FAQPELAR 228
            |. ..||||            |...|   |.|:..|.:|         ||.|...: .|.|...|
Human   188 GEFYKFGLEGIAAVLLGSRLGCLEAQVPPDTETFIRAVG---------SVFVSTLLTMAMPHWLR 243

  Fly   229 KL----RFRLFRPEVSEFFLDTVRQTLDYRRRENIHRNDLIQLLMELGEEGVKDA---------L 280
            .|    ..||.| :..:.|....|..   .|||       .:..|..|.:..||.         |
Human   244 HLVPGPWGRLCR-DWDQMFAFAQRHV---ERRE-------AEAAMRNGGQPEKDLESGAHLTHFL 297

  Fly   281 SFEQIAAQALV-----FFLAGFDTSSTTMSFCLYELALNPDVQERLRVEVLAVLKRNNQKLTYDS 340
            ..|::.||:::     ..|||.||.|.|:|:.||||:.:|:||..|..|:.|.|...:.  .|.|
Human   298 FREELPAQSILGNVTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSS--AYPS 360

  Fly   341 ---VQEMPYLDQVVAETLRKYPILPHLLRRSTK-----EYQIPNSNLILEPGSKIIIPVHSIHHD 397
               :.::|.|..||.|.||.||::|...|...|     :|.||.:.|       :.:..::...|
Human   361 ATVLSQLPLLKAVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTL-------VTLCHYATSRD 418

  Fly   398 PELYPDPEKFDPSRFEPEEIKARHPFAYLPFGEGPRNCIGERFGKLQVKVGLVYLLRDFKFSRSE 462
            |..:|:|..|.|:|:..|. ...||||.||||.|.|:|:|.|..:|::::.|..:|..|:. :.|
Human   419 PAQFPEPNSFRPARWLGEG-PTPHPFASLPFGFGKRSCMGRRLAELELQMALAQILTHFEV-QPE 481

  Fly   463 KTQIPLKFSSRNFLISTQEGVHLRMEGLER 492
            ....|::..:|..|:..:.   :.::.|:|
Human   482 PGAAPVRPKTRTVLVPERS---INLQFLDR 508

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a13	NP_610390.1	CYP6-like	67..484	CDD:410679	116/410 (28%)
CYP27B1	NP_000776.1	CYP27B1	68..503	CDD:410741	116/413 (28%)