Protein Alignment Cyp6a13 and Cyp27b1

DIOPT Version :10

• Sequence 1: NP_610390.1
• Gene: Cyp6a13 / 35837
• FlyBaseID: FBgn0033304
• Length: 493
• Species: Drosophila melanogaster
• Sequence 2: NP_034139.2
• Gene: Cyp27b1 / 13115
• MGIID: 1098274
• Length: 507
• Species: Mus musculus
• Alignment Length: 476
• Identity: 124/476 - (26%)
• Similarity: 204/476 - (42%)
• Gaps: 80/476 - (16%)

  Fly    45 GLGRDLHWTDINLRIYRKFRGVERY----CGYFTFMTKSLFIMDLELIRDIMIRD--------FS 97
            ||.| ||    .|:::    |..||    .|.|..: :::::.|..|:..::.::        ||
Mouse    57 GLSR-LH----ELQVH----GAARYGPIWSGSFGTL-RTVYVADPTLVEQLLRQESHCPERCSFS 111

  Fly    98 SFADRGLFHNVRDDPLTGNLLFLDGPEWRWLRQNLTQVFTSGKMKFMFPNMVE-VGEKLTQACRL 161
            |:|:    |..|.....| ||..||.||:.||..|..:....:....:...:: |...|.:..|.
Mouse   112 SWAE----HRRRHQRACG-LLTADGEEWQRLRSLLAPLLLRPQAAAGYAGTLDNVVRDLVRRLRR 171

  Fly   162 QVGE--------IEAKDLCARFTTDVIGSCAFG-----LECNSLQDPESQFRRMGRSVTQEPLHS 213
            |.|.        ::......:|..:.||:...|     ||.....|.|:....:|         |
Mouse   172 QRGRGSGLPGLVLDVAGEFYKFGLESIGAVLLGSRLGCLEAEVPPDTETFIHAVG---------S 227

  Fly   214 VLVQAFM-FAQPELARKL----RFRLFRPEVSEFFLDTVRQTLDYRRRENIHRND---------- 263
            |.|...: .|.|.....|    ..||.| :..:.|....|. ::.|..|...||.
Mouse   228 VFVSTLLTMAMPNWLHHLIPGPWARLCR-DWDQMFAFAQRH-VELREGEAAMRNQGKPEEDMPSG 290

  Fly   264 --LIQLLMELGEEGVKDALSFEQIAAQALVFFLAGFDTSSTTMSFCLYELALNPDVQERLRVEVL 326
              |...|.       ::.:|.:.|........|||.||.|.|:|:.||||:.:||||..|..|:.
Mouse   291 HHLTHFLF-------REKVSVQSIVGNVTELLLAGVDTVSNTLSWTLYELSRHPDVQTALHSEIT 348

  Fly   327 AVLKRNNQKLTYDSVQEMPYLDQVVAETLRKYPILPHLLRRSTKEYQIPNSNLILEPGSKIIIPV 391
            |..:.:.......::.::|.|..|:.|.||.||::|...|...::.::  .|.::...:.:.:..
Mouse   349 AGTRGSCAHPHGTALSQLPLLKAVIKEVLRLYPVVPGNSRVPDRDIRV--GNYVIPQDTLVSLCH 411

  Fly   392 HSIHHDPELYPDPEKFDPSRFEPEEIKARHPFAYLPFGEGPRNCIGERFGKLQVKVGLVYLLRDF 456
            ::...||..:|||..|:|:|:..|. ...||||.||||.|.|:|||.|..:|::::.|..:|..|
Mouse   412 YATSRDPTQFPDPNSFNPARWLGEG-PTPHPFASLPFGFGKRSCIGRRLAELELQMALSQILTHF 475

  Fly   457 KFSRSEKTQIPLKFSSRNFLI 477
            :. ..|...:|:|..:|..|:
Mouse   476 EV-LPEPGALPIKPMTRTVLV 495

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a13	NP_610390.1	CYP6-like	67..484	CDD:410679	117/454 (26%)
Cyp27b1	NP_034139.2	CYP27B1	68..502	CDD:410741	118/456 (26%)