Protein Alignment Cyp6a13 and Cyp3a41b

DIOPT Version :10

• Sequence 1: NP_610390.1
• Gene: Cyp6a13 / 35837
• FlyBaseID: FBgn0033304
• Length: 493
• Species: Drosophila melanogaster
• Sequence 2: NP_001098629.1
• Gene: Cyp3a41b / 100041375
• MGIID: 3714859
• Length: 504
• Species: Mus musculus
• Alignment Length: 513
• Identity: 171/513 - (33%)
• Similarity: 277/513 - (53%)
• Gaps: 65/513 - (12%)

  Fly     4 LLVLVFTVGLLLYVKLRWHYSYWSRRGVAGERPVYFRGNMSGLGRDLHWTDINLRIYRKFRGVER 68
            :|||::..|      .|.| ..:.::|:.|.:|:.|.|.:....:.| | ..::..|.|:   .:
Mouse    18 ILVLLYRYG------TRTH-GLFKKQGIPGPKPLPFLGTVLNYYKGL-W-KFDMECYEKY---GK 70

  Fly    69 YCGYFTFMTKSLFIMDLELIRDIMIRD-FSSFADRGLFHNV----------RDDPLTGNLLFLDG 122
            ..|.|........|.|.|:|::::::: ||.|.:|..|..|          :|:
Mouse    71 TWGLFDGQMPLFVITDPEMIKNVLVKECFSVFTNRREFGPVGIMSKAISISKDE----------- 124

  Fly   123 PEWRWLRQNLTQVFTSGKMKFMFPNMVEVGEKLTQACRLQVGE----IEAKDLCARFTTDVIGSC 183
             ||:..|..|:..|||||:|.|||.:.:.|:.|.:.. :|..|    :..||:...::.|||.|.
Mouse   125 -EWKRYRALLSPTFTSGKLKEMFPVIEQYGDILVKYL-MQEAEKGKPVTMKDVLGAYSIDVITST 187

  Fly   184 AFGLECNSLQDPESQFRRMGRSVTQ----EPL-HSVLVQAFMFAQPELARKLRFRLFRPEVSEFF 243
            :||:..:||.:||..|....:.:.:    :|| .||::  |.|..| :...|...:|..:..|||
Mouse   188 SFGVNVDSLNNPEDPFVEKAKGILRVDFFDPLVFSVVL--FPFLTP-VYEMLNICMFPKDSIEFF 249

  Fly   244 LDTVRQ----TLDYRRRENIHRNDLIQLLMELGEEGVKD-----ALSFEQIAAQALVFFLAGFDT 299
            ...|.:    .||.:::   ||.|.:||:|. .....||     |||..:|.||::||..||::|
Mouse   250 KKFVNRMKESRLDSKQK---HRVDFLQLMMN-AHNNSKDKDSHKALSDMEITAQSIVFIFAGYET 310

  Fly   300 SSTTMSFCLYELALNPDVQERLRVEVLAVLKRNNQKLTYDSVQEMPYLDQVVAETLRKYPILPHL 364
            :|:|:||.||.||.:||:|::|:.|:...|. |....|||:|.||.|||.|:.||||.|||...|
Mouse   311 TSSTLSFTLYCLATHPDIQKKLQEEIDETLP-NKAPPTYDTVMEMEYLDMVLNETLRLYPIGNRL 374

  Fly   365 LRRSTKEYQIPNSNLILEPGSKIIIPVHSIHHDPELYPDPEKFDPSRFEPEEIKARHPFAYLPFG 429
            .|...|:.::  :.:.:..||.::||.:::||||:.:|:||:|.|.||..|...:..|:.|:|||
Mouse   375 ERFCKKDVEL--NGVYIPKGSTVMIPSYALHHDPQHWPEPEEFQPERFSKENKGSIDPYLYMPFG 437

  Fly   430 EGPRNCIGERFGKLQVKVGLVYLLRDFKFSRSEKTQIPLKFSSRNFLISTQEGVHLRM 487
            .|||||||.||..:.:|:.|..::::|.|...::||||||. ||..|:..::.:.|::
Mouse   438 IGPRNCIGMRFAFMTMKLALTKVMQNFSFQPCQETQIPLKL-SRQGLLQPEKPIVLKV 494

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a13	NP_610390.1	CYP6-like	67..484	CDD:410679	155/445 (35%)
Cyp3a41b	NP_001098629.1	CYP3A	67..493	CDD:410743	156/452 (35%)