DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp6a14 and CYP709B3

DIOPT Version :9

Sequence 1:	NP_001286199.1	Gene:	Cyp6a14 / 35835	FlyBaseID:	FBgn0033302	Length:	509	Species:	Drosophila melanogaster
Sequence 2:	NP_194501.1	Gene:	CYP709B3 / 828885	AraportID:	AT4G27710	Length:	518	Species:	Arabidopsis thaliana

Alignment Length:	506	Identity:	121/506 - (23%)
Similarity:	229/506 - (45%)	Gaps:	55/506 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MLFTIALVGVVLGLAYSLHIKIFSYWKRKGVPHETPLPIVGNMRGIVKKY----------HFRDI 55
            :||.::.:.....:.....:.:...:|::|:.......:.||:..|.|..          :..||
plant    15 LLFVVSKIWKACWILLLRPLMLSKRFKKQGISGPKYKILYGNLSEIKKMKKEADLCVLDPNSNDI 79

  Fly    56 NQRIYKKF-KGQGPIAGMYMFF---KRTALITDLDFIKQVMIKDFSYFQDRGAFTNPRDDPLTGH 116
            ..|::.:: :........::|:   |.|..|::.:..|||:...|      |....|...|....
plant    80 FPRVFPQYHQWMSQYGDTFLFWTGTKPTIYISNHELAKQVLSSKF------GFTIIPVKRPEVFI 138

  Fly   117 LFA-----LEGEEWRAMRHKLTPVFTSGKIKQMSKVIVDVGLRLGDAMDKAVKEAKVEEGNVEIK 176
            ||.     ::|::|...|..|.|.|:..::|.|::.:.|..||:.:...|..:..:|.. .:||.
plant   139 LFGKGLSFIQGDDWIRHRRILNPAFSMDRLKAMTQPMGDCTLRIFEEWRKQRRNGEVLI-KIEIS 202

  Fly   177 DLCARFTTDVIGSCAFGLECNSLQDPSAEFRQKGREIFTRRRHSTLVQSFIFTNARLARKLRIKV 241
            ....:.|.|:|.:.|||    |......|..:...|: .:...|:|...||.....|.....:|:
plant   203 KEFHKLTADIIATTAFG----SSYAEGIELCRSQTEL-EKYYISSLTNVFIPGTQYLPTPTNLKL 262

  Fly   242 LPDDLTQFFMSTVKNTVDYRLKNGIKRNDFIEQMIEL---RAEDQEAAKKGQGIDLSHGLTLEQM 303
            .  :|.:...:::|..:|.|||:..|...:.:.::.:   .|:..|..:|         :.::::
plant   263 W--ELHKKVKNSIKRIIDSRLKSKCKTYGYGDDLLGVMLTAAKSNEYERK---------MRMDEI 316

  Fly   304 AAQAFVFFVAGFETSSSTMSLCLYELALQPDIQQRLREEIESVLANVDGGEL--NYDVLAQMTYL 366
            ..:...|:.||..|:|..::.....|:|....|::||||:    .|..|.:.  :.|..:::..:
plant   317 IEECKNFYYAGQGTTSILLTWTTMLLSLHQGWQEKLREEV----FNECGKDKIPDTDTFSKLKLM 377

  Fly   367 DQVLSETLRKHPLLPHLIRETTKDYQIPNSDIVLDKGILALIPVHNIHHDPEIYPE-PEKFDPSR 430
            :.||.|:||.:..:..:.||.|:|.::.:.:|  .||...:||:..:|.|..|:.| .|:|:|.|
plant   378 NMVLMESLRLYGPVIKISREATQDMKVGHLEI--PKGTSIIIPLLKMHRDKAIWGEDAEQFNPLR 440

  Fly   431 FDPE-EVKNRHPMAYLPFGDGPRNCIGLRFGKIQAKIGLVSLLRRFKFSVS 480
            |:.. .....||.|.|||..|||.||...|..::||..|..:|::|:.|:|
plant   441 FENGISQATIHPNALLPFSIGPRACIAKNFAMVEAKTVLTMILQQFQLSLS 491

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a14	NP_001286199.1	p450	32..506	CDD:306555	117/475 (25%)
CYP709B3	NP_194501.1	p450	9..517	CDD:299894	121/506 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm3438
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810