DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp6a14 and CYP705A23

DIOPT Version :9

Sequence 1:	NP_001286199.1	Gene:	Cyp6a14 / 35835	FlyBaseID:	FBgn0033302	Length:	509	Species:	Drosophila melanogaster
Sequence 2:	NP_188649.1	Gene:	CYP705A23 / 821557	AraportID:	AT3G20140	Length:	510	Species:	Arabidopsis thaliana

Alignment Length:	542	Identity:	116/542 - (21%)
Similarity:	207/542 - (38%)	Gaps:	117/542 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 LVGVVLGLAYSLHIKIFSYWKRKGV--------PHETPLPIVGNMRGIVKKYHFRDINQRIYKKF 63
            |:.::|.|.|.|      ::|:..|        |....|||:|::..:......:.: |::..|:
plant    17 LLCILLLLCYPL------FFKKPKVSQDGFGLPPSPLSLPIIGHLHLLFSNLTHKSL-QKLSSKY 74

  Fly    64 KGQGPIAGMYMFFKRTALITDLDFIKQVMIKDFSYFQDRGAFTN-------PRDDPLT----GHL 117
               ||:  :|:......:|    |:....:   :|...||...|       |.::.|.    |..
plant    75 ---GPL--LYLRIFNVPII----FVSSASV---AYEIFRGHDVNISFRGNPPIEESLLVGSFGFF 127

  Fly   118 FALEGEEWRAMRHKLTPVFTSGKIKQMSKVIVDVGLRLGDA--------MDKAVKEAKVEEGNVE 174
            .|..|:.|:.|:..:.......:..|.|:     |:| .||        :|||:|:..||.|...
plant   128 TAPYGDYWKFMKKVMVTKLLGPQALQRSR-----GIR-ADALERFYMNLLDKAMKKESVEIGKET 186

  Fly   175 IKDLCARFTTDVIGSCAFGLECNSLQDPSAEFRQKGREIFTRRRHSTLVQSFIFTNARLARKL-R 238
            :|     ...|.|        |..:.         ||........:..|:..:..:..|.:|: .
plant   187 MK-----LIYDSI--------CKMIM---------GRNFSEENGEAERVRGLVTESTALTKKIFM 229

  Fly   239 IKVLPDDLTQFFMSTVKNTV-DYRLKNGIKRNDFIEQMIELRAEDQEAAKKGQGIDLSHGL---- 298
            ..||...|.:..:|..|..: |.       .|.|.|.:.....|.:|...:.|.:|:...|
plant   230 ANVLHKPLKKLGISLFKKEIMDV-------SNSFDELLERFLVEHEEKLNEDQDMDMMGVLLAAC 287

  Fly   299 ---------TLEQMAAQAFVFFVAGFETSSSTMSLCLYELALQPDIQQRLREEIESVLANVDGGE 354
                     |...:.:......|||.:||.......:.|:..:|.:.:::||||.||:...   .
plant   288 RDKNAECKITRNHIKSLFVDLVVAGTDTSRHATQWTMAEIINKPKVLEKVREEIYSVVGRT---R 349

  Fly   355 LNYDV-LAQMTYLDQVLSETLRKHPLLPHLIRETTKDYQI------PNSDIVLDKGILALIPVHN 412
            |..:. |..:.||...:.|.||.||..|...|...:.:.:      .|:.:|::        .:.
plant   350 LVQETDLPSLPYLQATVKEGLRLHPPGPLFARTAREGFSVGGFYVPENTPLVVN--------AYA 406

  Fly   413 IHHDPEIYPEPEKFDPSRF--DPEEVKNRHPMAYLPFGDGPRNCIGLRFGKIQAKIGLVSLLRRF 475
            :..||..:.:|.:|.|.||  ..:|.:..|.:.|:|||.|.|.|.|:....|.....:..:::.|
plant   407 MMRDPGSWEDPNEFKPERFLGSGKEDEREHGLKYIPFGSGRRGCPGINLAYILVGTAIGVMVQCF 471

  Fly   476 KFSVSNRTDVPLIFSKKSFLLT 497
            .:.:.. ..|.:..::.|.:||
plant   472 DWKIKG-NKVNMEEARGSLVLT 492

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a14	NP_001286199.1	p450	32..506	CDD:306555	109/509 (21%)
CYP705A23	NP_188649.1	p450	26..504	CDD:386267	113/533 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D467733at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920