DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp6a14 and CYP72A7

DIOPT Version :9

Sequence 1:	NP_001286199.1	Gene:	Cyp6a14 / 35835	FlyBaseID:	FBgn0033302	Length:	509	Species:	Drosophila melanogaster
Sequence 2:	NP_188079.1	Gene:	CYP72A7 / 820689	AraportID:	AT3G14610	Length:	512	Species:	Arabidopsis thaliana

Alignment Length:	484	Identity:	118/484 - (24%)
Similarity:	209/484 - (43%)	Gaps:	66/484 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 KRKGVPHETPLPIVGNM-RGIVKKYHFR--------DINQRI----YKKFKGQGPIAGMYMFFKR 78
            ||:|:......|:||:: |.:......|        ||..|:    .|.....|....:::....
plant    39 KRQGLTGTPYTPLVGDIKRNVDMMMEARSKPINVTDDITPRLLPLALKMLNSHGKTFFIWIGPLP 103

  Fly    79 TALITDLDFIKQVM--IKDFSYFQDRGAFTNPRDDPLTGHLFALEGEEWRAMRHKLTPVFTSGKI 141
            |.:||:.:.||:|.  :.||     ..|.|.|....|.|.|.:.:|::|.:.|..:.|.|...||
plant   104 TIVITNPEQIKEVFNKVNDF-----EKASTFPLIRLLAGGLASYKGDKWASHRRIINPAFHLEKI 163

  Fly   142 KQM--------SKVIVDVGLRLGDAMDKAVKEAKVEEGNVEIKDLCARFTTDVIGSCAFGLECNS 198
            |.|        |:|:........|      ||:.:|   |::.......|.|||...|||   :|
plant   164 KNMIPAFYHCCSEVVCQWEKLFTD------KESPLE---VDVWPWLVNMTADVISHTAFG---SS 216

  Fly   199 LQDPSAEFRQKGR--EIFTRRRHSTLVQSFIFTNARLARKLRIKVLPDDLTQFFMSTVKNTVDYR 261
            .::....|:.:|.  |:..:....:.:....|...:..|  |:|.:..::.......|......|
plant   217 YKEGQRIFQLQGELAELIAQAFKKSYIPGSRFYPTKSNR--RMKAIDREVDVILRGIVSKREKAR 279

  Fly   262 LKNGIKRNDFIEQMIELRAEDQEAAKKGQGIDLSHGLTLEQMAAQAFVFFVAGFETSSSTMSLCL 326
            .......:|.:..::|..:|:.:          .:|:::|.:..:..:|:.||.||:|..:...:
plant   280 EAGEPANDDLLGILLESNSEESQ----------GNGMSVEDVMKECKLFYFAGQETTSVLLVWTM 334

  Fly   327 YELALQPDIQQRLREEIESVLANVDGGELN---YDVLAQMTYLDQVLSETLRKHPLLPHLIRETT 388
            ..|:...|.|.|.|||:..||     ||.|   .:.|..:..:..:.:|.||.:|.:..|.|...
plant   335 VLLSHHQDWQARAREEVMQVL-----GENNKPDMESLNNLKVMTMIFNEVLRLYPPVAQLKRVVN 394

  Fly   389 KDYQIPNSDIVLDKGILALIPVHNIHHDPEIY-PEPEKFDPSRF-DPEEVKNRHPMAYLPFGDGP 451
            |:.::  .::.|..||...:|...:..|.|:: .:...|.|.|| |......::.:::.|||.||
plant   395 KEMKL--GELTLPAGIQIYLPTILVQRDTELWGDDAADFKPERFRDGLSKATKNQVSFFPFGWGP 457

  Fly   452 RNCIGLRFGKIQAKIGLVSLLRRFKFSVS 480
            |.|||..|..::||:.:..:|::|.|.:|
plant   458 RICIGQNFAMLEAKMAMALILQKFSFELS 486

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a14	NP_001286199.1	p450	32..506	CDD:306555	115/479 (24%)
CYP72A7	NP_188079.1	p450	21..512	CDD:299894	118/484 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm3438
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810