DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp6a14 and CYP709B1

DIOPT Version :9

Sequence 1:	NP_001286199.1	Gene:	Cyp6a14 / 35835	FlyBaseID:	FBgn0033302	Length:	509	Species:	Drosophila melanogaster
Sequence 2:	NP_566092.1	Gene:	CYP709B1 / 819310	AraportID:	AT2G46960	Length:	519	Species:	Arabidopsis thaliana

Alignment Length:	517	Identity:	137/517 - (26%)
Similarity:	234/517 - (45%)	Gaps:	70/517 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MLFTIALVGVVLGLAYSLHI-KIFS--YW---------KRKGVPHETPLPIVGNMRGIVK---KY 50
            |...|.|..:||.|...|.| |.|.  .|         |.:|:.........||:..|.|   :.
plant     1 MGLVIFLALIVLILIIGLRIFKAFMILVWHPFVLTRRLKNQGISGPNYRIFYGNLSEIKKMKRES 65

  Fly    51 HF-------RDINQRI---YKKFKGQGPIAGMYMFFKRT---ALITDLDFIKQVMIKDFSYFQDR 102
            |.       .||..||   |:|:..|  ....::::..|   ..|:|.:..|.::.....:|...
plant    66 HLSILDPSSNDIFPRILPHYQKWMSQ--YGETFLYWNGTEPRICISDPELAKTMLSNKLGFFVKS 128

  Fly   103 GAFTNPRDDPLTGH--LFALEGEEWRAMRHKLTPVFTSGKIKQMSKVIVDVGLRLGDAMDKAVKE 165
            .|  .|....|.|.  |..:||.:|...|..|.|.|:..::|.|:.|:||..|::.:...|...:
plant   129 KA--RPEAVKLVGSKGLVFIEGADWVRHRRILNPAFSIDRLKIMTTVMVDCTLKMLEEWRKESTK 191

  Fly   166 AKVEEGNV--EIKDLCARFTTDVIGSCAFGLECNSLQDPSAEFRQKGREIFTRRRHST-LVQSFI 227
            .:.|...:  |:.:...|.|.|:|.:.|||   :|..:....||.   ::..:|.::| |.|..|
plant   192 EETEHPKIKKEMNEEFQRLTADIIATSAFG---SSYVEGIEVFRS---QMELKRCYTTSLNQVSI 250

  Fly   228 FTNARLARKLRIKVLPDDLTQFFMSTVKNTVDYRLKNGIKRNDFIEQM--IELRAEDQEAAKKGQ 290
            .....|.....|:|.  .|.:...:::|..:..||::   ::|:.:.:  |.|:|.:.|..::
plant   251 PGTQYLPTPSNIRVW--KLERKMDNSIKRIISSRLQS---KSDYGDDLLGILLKAYNTEGKER-- 308

  Fly   291 GIDLSHGLTLEQMAAQAFVFFVAGFETSSSTMSLCLYELALQPDIQQRLREEIESVLANVDGGEL 355
                  .:::|::..:...||..|.||:|:.::.....|:|..|.|::|||||....    |.|.
plant   309 ------KMSIEEIIHECRTFFFGGHETTSNLLAWTTMLLSLHQDWQEKLREEIFKEC----GKEK 363

  Fly   356 NYD--VLAQMTYLDQVLSETLRKHPLLPHLIRETTKDYQIPNSDIVLDKGILALIPVHNIHHDPE 418
            ..|  ..:::..::.|:.|:||.:..:..|.||.:.:.::  .|:.:.||...:||:..:|.|..
plant   364 TPDSETFSKLKLMNMVIMESLRLYGPVSALAREASVNIKL--GDLEIPKGTTVVIPLLKMHSDKT 426

  Fly   419 IY-PEPEKFDPSRF--DPEEVKNRHPMAYLPFGDGPRNCIGLRFGKIQAKIGLVSLLRRFKF 477
            :: .:.:||:|.||  ......| ||.|.|.|..|||.|||..|..|:||..|..:|:||:|
plant   427 LWGSDADKFNPMRFANGVSRAAN-HPNALLAFSVGPRACIGQNFVMIEAKTVLTMILQRFRF 487

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a14	NP_001286199.1	p450	32..506	CDD:306555	124/474 (26%)
CYP709B1	NP_566092.1	p450	32..517	CDD:299894	126/486 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm3438
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810