Protein Alignment Cyp6a14 and Cyp3a57

DIOPT Version :9

• Sequence 1: NP_001286199.1
• Gene: Cyp6a14 / 35835
• FlyBaseID: FBgn0033302
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_001093650.1
• Gene: Cyp3a57 / 622127
• MGIID: 3646373
• Length: 503
• Species: Mus musculus
• Alignment Length: 483
• Identity: 154/483 - (31%)
• Similarity: 254/483 - (52%)
• Gaps: 51/483 - (10%)

  Fly    26 WKRKGVPHETPLPIVGN----MRGIVKKYHFRDINQRIYKKFKGQGPIAGMYMFFKRTALITDLD 86
            :|:.|:|...|||:.||    :.|:.|      .:...|||:   |.|.|.|...:....|.|.:
Mouse    33 FKKLGIPGPKPLPLFGNIINYLDGMWK------FDDDCYKKY---GKIWGFYEGPQPILAIMDPE 88

  Fly    87 FIKQVMIKD-FSYFQDRGAFTNPRDDP---LTGHLFALEGEEWRAMRHKLTPVFTSGKIKQMSKV 147
            .||.|::|: :|.|.:|..|     .|   |...:...|.|||:.:|..|:|.|||.|:|:|..:
Mouse    89 IIKIVLVKECYSVFTNRRPF-----GPVGFLKKSITISEDEEWKRLRTLLSPTFTSSKLKEMFPI 148

  Fly   148 IVDVGLRLGDAMDKAVKEAKVEEGNVEIKDLCARFTTDVIGSCAFGLECNSLQDPSAEFRQKGRE 212
            :    .:.||.:.:.::..:.:|..:.:||:...::.|||...:.|:..:||.:|...|.||.::
Mouse   149 M----RQYGDILVRNLRREEEKEEPINMKDIFGAYSMDVITGTSCGVNIDSLNNPQDPFVQKIKK 209

  Fly   213 IFTRRRHSTLVQS---FIFTNARLARKLRIKVLPDDLTQFFMSTV----KNTVDYRLKNGIKRND 270
            |...:.....:.|   |.|... :...|.:.:.|.....||...|    |:.:||..||   |.|
Mouse   210 ILKFKFFDPFLLSVVLFPFLTP-IYEMLNLSIFPRQSMNFFKKFVKKMKKDRLDYNQKN---RVD 270

  Fly   271 FIEQMIELR-AEDQEAAKKGQGIDLSHGLTLEQMAAQAFVFFVAGFETSSSTMSLCLYELALQPD 334
            |::.|:..: ::.||:.|         .|:..:||||..:|...|::.:|:::|..:||||..||
Mouse   271 FLQLMMNTQNSKGQESLK---------ALSDLEMAAQTLIFIFGGYDGTSTSISFIMYELATHPD 326

  Fly   335 IQQRLREEIESVLANVDGGELNYDVLAQMTYLDQVLSETLRKHPLLPHLIRETTKDYQIPNSDIV 399
            :|::|::||:..|.|  ...:.||.|..|.|||.|::|:||.:|::..:.|.:.||.:|  ..:.
Mouse   327 VQKKLQDEIDRALPN--KAPVTYDALMDMEYLDMVVNESLRLYPVVSRIDRFSKKDVEI--HGVF 387

  Fly   400 LDKGILALIPVHNIHHDPEIYPEPEKFDPSRFDPEEVKNRHPMAYLPFGDGPRNCIGLRFGKIQA 464
            :.||.:.:||::.:|.|||.:||||.|.|.||..|...|..|..|:|||:|||||||:||..|..
Mouse   388 IPKGTIVMIPIYPLHRDPEYWPEPEDFCPERFSKENKGNIDPYIYMPFGNGPRNCIGMRFALISV 452

  Fly   465 KIGLVSLLRRFKFSVSNRTDVPLIFSKK 492
            |:.:..:|:.|.......|.:|:..|::
Mouse   453 KLAVTGVLQNFTVQPCEETQIPVKISRQ 480

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a14	NP_001286199.1	p450	32..506	CDD:306555	152/477 (32%)
Cyp3a57	NP_001093650.1	p450	39..493	CDD:278495	152/477 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X40
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.820