Protein Alignment Cyp6a14 and Cyp4f17

DIOPT Version :10

• Sequence 1: NP_610389.3
• Gene: Cyp6a14 / 35835
• FlyBaseID: FBgn0033302
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_001178915.1
• Gene: Cyp4f17 / 500801
• RGDID: 1561655
• Length: 524
• Species: Rattus norvegicus
• Alignment Length: 511
• Identity: 135/511 - (26%)
• Similarity: 217/511 - (42%)
• Gaps: 99/511 - (19%)

  Fly    33 HETPLPIVGNMRGIVKKYHFRDIN-----------QRIYKKFKG---QGPIAGMYMFFKRTALIT 83
            :|..|.::..|     .:.|:||:           :.|:.||.|   |.|.|
  Rat    70 NEEGLQLLAEM-----SHQFQDIHLCWIGIFYPILRLIHPKFIGPILQAPAA------------- 116

  Fly    84 DLDFIKQVMIKDFSYFQDRGAFTNPRDDPLTGHLFALEGEEWRAMRHKLTPVFTSGKIKQMSKVI 148
                   |..|:..::    .|..|.   |...|....||:|...|..|||.|....:|...|
  Rat   117 -------VAPKEMIFY----GFLKPW---LGDGLLVSAGEKWSRQRRLLTPAFHFDILKPYVK-- 165

  Fly   149 VDVGLRLGDAMDKAVK--EAKVE------EGNVEIKDLCARFTTDVIGSCAFGLECNSLQDPS-- 203
                     ..:|:|.  .||.:      ...:::.:..:..|.|.:..|.|..:.|..:.||
  Rat   166 ---------NFNKSVNIMHAKWQRLTAKGSARLDMFEHISLMTLDSLQKCVFSFDSNCQESPSEY 221

  Fly   204 -AEFRQKGREIFTRRRHSTLVQSFIFTNARLARKLRIKVLPDDLTQFFMSTV---------KNTV 258
             |..::....|..|.....|...|::......|:.|...   ||...|...|         ..:|
  Rat   222 IAAIQELSSLIVKRHHQPFLYMDFLYYLTADGRRFRKAC---DLVHNFTDAVIRERRRTLSSQSV 283

  Fly   259 DYRLKNGIKRN--DFIEQMIELRAEDQEAAKKGQGIDLSHGLTLEQMAAQAFVFFVAGFETSSST 321
            |..||:..|..  |||:.::        .||...|.:||.    |.:.|:|..|...|.:|::|.
  Rat   284 DEFLKSKTKSKTLDFIDVLL--------LAKDEHGKELSD----EDIRAEADTFMFGGHDTTASA 336

  Fly   322 MSLCLYELALQPDIQQRLREEIESVLANVDGGELNYDVLAQMTYLDQVLSETLRKHPLLPHLIRE 386
            :|..||.||..|:.|:|.|:|:..:|.:.:..|:.:|.|.|:.:|...:.|:||.||.:..:.|.
  Rat   337 LSWILYNLARHPEHQERCRQEVRELLRDREPEEIEWDDLTQLPFLTMCIKESLRLHPPVTVISRC 401

  Fly   387 TTKDYQIPNSDIVLDKGILALIPVHNIHHDPEIYPEPEKFDPSRFDPEEVKNRHPMAYLPFGDGP 451
            .|:|..:|:.. |:.||...:|.:..:||:|.::|:||.:||.|||.|..:.|.|:|::||..||
  Rat   402 CTQDVVLPDGR-VIPKGNDCIISIFGVHHNPSVWPDPEVYDPFRFDSENPQKRSPLAFIPFSAGP 465

  Fly   452 RNCIGLRFGKIQAKIGLVSLLRRFKFSVSNRTDVPLIFSKKSFLLTTNDGIYLKVE 507
            |||||..|...:.|:.:...|.||:....::..    ..|...:|....|::|:||
  Rat   466 RNCIGQTFAMNEMKVAVALTLLRFRLLPDDKEP----RRKPELILRAEGGLWLRVE 517

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a14	NP_610389.3	CYP6-like	65..503	CDD:410679	123/462 (27%)
Cyp4f17	NP_001178915.1	CYP4F	74..515	CDD:410772	131/503 (26%)